Treatment Response to Rehabilitation in Patients With Schizophrenia
NCT ID: NCT00063336
Last Updated: 2013-11-08
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
46 participants
INTERVENTIONAL
2001-12-31
2005-11-30
Brief Summary
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Detailed Description
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Two studies will be conducted. The first will investigate the relationship of symptoms and neurocognitive variables at study entry to psychosocial and vocational status 2 years later. The second study will investigate the relationship of symptoms and neurocognitive variables at study entry to treatment response in patients assigned to either a cognitive remediation track or a computer skills track as part of their rehabilitation treatment.
Both the cognitive remediation and computer skills training programs will last 4 to 6 months. Participants will be assessed pre- and post-treatment. Neuropsychological, psychosocial and vocational status will be measured.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
Study Groups
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1
Participants will receive cognitive remediation treatment.
Cognitive Remediation
A computerized cognitive rehabilitation treatment with day-program activities
2
Participants will receive computer-skills training.
Computer-skills training
A computerized cognitive rehabilitation treatment with day-program activities
Interventions
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Cognitive Remediation
A computerized cognitive rehabilitation treatment with day-program activities
Computer-skills training
A computerized cognitive rehabilitation treatment with day-program activities
Eligibility Criteria
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Inclusion Criteria
* In need of intensive outpatient care
* Treatment with atypical antipsychotic medication for a minimum of 6 months prior to study entry
Exclusion Criteria
* Mental retardation (IQ less than 70)
* Traumatic brain injury with loss of consciousness
* Presence or history of any neurological illness that may affect brain physiology
* Lack of proficiency in English
* Concurrent substance abuse and/or dependence
18 Years
ALL
No
Sponsors
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National Institute of Mental Health (NIMH)
NIH
Hartford Hospital
OTHER
Responsible Party
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Schizophrenia Rehabilitation Program, Institutes of Living
Principal Investigators
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Matthew M. Kurtz, PhD
Role: PRINCIPAL_INVESTIGATOR
Schizophrenia Rehabilitation Program, Institutes of Living
Locations
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Schizophrenia Rehabilitation Program, Institutes of Living
Hartford, Connecticut, United States
Countries
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Other Identifiers
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