Efficacy of Social Cognition Training in Schizophrenia

NCT ID: NCT00587561

Last Updated: 2025-10-03

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

51 participants

Study Classification

INTERVENTIONAL

Study Start Date

2008-01-31

Study Completion Date

2023-12-31

Brief Summary

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The term social cognition refers to how social information is processed. Individuals with schizophrenia and schizoaffective disorder have been shown to have significant deficits in social cognition. Moreover, it has been speculated that these deficits may in turn have a negative impact on their overall functioning. Behavioral interventions targeting social cognition are just beginning to emerge, and there is a need to evaluate their efficacy.

Objectives:

This is a small trial evaluating the efficacy of social cognition interaction training (SCIT) an experimental behavioral treatment for improving social cognition in schizophrenia.

Research Design and Methodology:

Approximately 48 participants with schizophrenia-spectrum disorders will be randomized into one of two conditions: 1) a 20 to 24 session manualized social cognition interaction training group (SCIT), or 2) wait-list control. Pre-and post-group therapy assessments of symptoms, social cognition, basic cognition, and community function will be conducted. Data obtained from this study will allow us to determine the efficacy of SCIT training in improving symptom, cognitive, and functional measures.

Detailed Description

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Conditions

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Schizophrenia

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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1 Social Cognition Interaction Training

Will receive 20-26 sessions of a manualized group treatment called Social Cognition Interaction Training

Group Type EXPERIMENTAL

Social Cognition Interaction Training

Intervention Type BEHAVIORAL

manualized group therapy

2 Wait List Control

Wait list control; 6 months of treatment as usual followed by Social Cognition Interaction Training group

Group Type OTHER

WLC

Intervention Type BEHAVIORAL

wait-list control for 6 months, followed by the experimental group therapy

Interventions

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Social Cognition Interaction Training

manualized group therapy

Intervention Type BEHAVIORAL

WLC

wait-list control for 6 months, followed by the experimental group therapy

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* diagnosis of schizophrenia or schizoaffective disorder
* Age between 18 and 65
* minimum of 30 days since discharge from last hospitalization
* minimum of 30 days since last change in psychiatric medications
* no housing changes in the past 30 days

Exclusion Criteria

* current diagnosis of alcohol or substance abuse/dependence
* history of brain trauma or neurological disease
* mental retardation or developmental disability
* auditory or visual impairment that would interfere with study procedures
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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VA Connecticut Healthcare System

FED

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Joanna Fiszdon, Ph.D.

Role: PRINCIPAL_INVESTIGATOR

VA Connecticut Heathcare System and Yale University

Locations

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Connecticut Mental Health Center

New Haven, Connecticut, United States

Site Status

VA Connecticut Healthcare System

West Haven, Connecticut, United States

Site Status

Countries

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United States

References

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Fiszdon JM, Dixon HD, Davidson CA, Roberts DL, Penn DL, Bell MD. Efficacy of social cognition and interaction training in outpatients with schizophrenia spectrum disorders: randomized controlled trial. Front Psychiatry. 2023 Aug 4;14:1217735. doi: 10.3389/fpsyt.2023.1217735. eCollection 2023.

Reference Type RESULT
PMID: 37599886 (View on PubMed)

Other Identifiers

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D4628W

Identifier Type: -

Identifier Source: secondary_id

JMF0005

Identifier Type: -

Identifier Source: org_study_id

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