Speed of Glucose Absorption

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

16 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-07-16

Study Completion Date

2024-11-15

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The purpose of this study is to look at how fast commercially available supplements containing carbohydrate can get into the bloodstream. If carbohydrate, in the form of glucose, gets into the blood faster, this can provide an instant energy source and help fuel the body during exercise. We will be testing three supplements, namely Voom Pocket Rocket, SIS Go Isotonic Energy Gel, and Maurten Gel 160. Each participant will complete all three conditions, consuming one of each supplement at random per condition. The study requires participation from male runners, cyclists and triathletes who are aged between 18-35.

Each visit will take approximately 1 hour and 30 minutes, and three experimental visits per participant. The study will involve frequent blood sampling and the continuous monitoring of gas exchange (oxygen/carbon dioxide). Blood sampling via cannulation will be used to analyse the lactate, glucose, and insulin content of the blood. Gas exchange will measure the oxygen breathed in and carbon dioxide breathed out throughout the study.

The investigators plan to carry out the study on 16 participants who will be a mix of male runners, cyclists and triathletes.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Efficacy of a Carbohydrate Drink on Speed, Agility and Power in School Going Children

NCT02428127

Growth and Development

COMPLETED NA

Superstarch and Physical/Cognitive Performance Following a Simulated Soccer Game

NCT02667340

Effect of Superstarch on Soccer Performance

UNKNOWN NA

Assessment of the Glycemic Responses to Nutritional Products-INQ-2526

NCT07243743

Glycemic Response

COMPLETED NA

Exogenous Oxidation of Fructose-glucose Mixtures During Running

NCT03731065

Exercise

COMPLETED NA

Effect of Glycogen Replenishment on Time Trial Performance Following a Glycogen Lowering Exercise

NCT03682861

Carbohydrate Metabolism

UNKNOWN NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

The aim of this study is to investigate and compare the speed of delivery of three commercially available carbohydrate supplements during a 1 hour modified glucose tolerance test. This study will be a randomised double-blind crossover in design. Participants will be required to attend the Human Performance Laboratory at Lancaster University on three separate visits. During each visit, participants will be required to consume one of three commercially available carbohydrate supplements, namely Maurten Gel 160 (MAU), Voom Pocket Rocket Electro Energy Bar (PR), and SIS Go Isotonic Energy Gel (SIS). Each consumable will be blinded to both the researchers and participants, flavoured the same (lemon and lime) and placed into identical packaging with anonymised labelling to minimise the risk of bias. The supplements will be matched for carbohydrate content (45 grams). Blinding of supplements will be completed offsite by people not in the research team and followed strict food and hygiene protocols. Each participant will complete all three conditions, consuming one of each supplement at random per condition.

Each visit will involve frequent venous blood sampling for glucose, lactate and insulin. An anterograde venous cannula will be inserted into a vein in the antecubital fossa of the arm by a qualified member of the research team. This is a less invasive alternative to an arterial cannula whilst still allowing for accurate metabolic measures to be taken. This method is also less painful than inserting a retrograde cannula which can cause significant discomfort.

Once the anterograde venous cannula is inserted and secured in place, a resting measurement of blood will be taken (1ml of blood taken to measure glucose and lactate, and 3ml for insulin). Participants will then be required to consume one of the three carbohydrate energy supplements. Once the supplement had been consumed, continuous gas analysis will begin to analyse gas exchange to non-invasively measure substrate utilisation. This signals the start of the test, and a timer will be set for 1 hour.

Throughout the test, blood sampling will be taken in frequent intervals. 1ml of blood sampled every 5 minutes to check for glucose and lactate, and 3ml of blood sampled every 10 minutes for insulin. Gas exchange will be continuously measured to non-invasively measure substrate utilization in the muscle via indirect calorimetry which determines energy expenditure by measuring the body's oxygen consumption and carbon dioxide production. The measurement is based on the assumption that the volume of oxygen (VO2) consumed is used to oxidise fuels, and the volume of carbon dioxide (VCO2) produced is a by-product of substrate utilisation.

After the study visit, analysis will be conducted assessing how each of the three supplements effect blood glucose, blood lactate, insulin, and gas exchange.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Healthy Nutrition, Healthy

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

This will be a double-blind randomised crossover design. There will be 1 group of participants who will complete all three conditions at random:

Condition 1 - consume Voom Pocket Rocket. Condition 2 - consume SIS Isotonic Energy Gel. Condition 3 - consume Maurten Gel 160.

All participants will undergo the same measures - blood sampling for blood glucose, blood lactate, electrolytes and insulin, and monitoring of gas exchange during each study visit.

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

DOUBLE

Participants Investigators

Both the participants and investigators will be blinded to what supplement they are consuming on each visit. Each supplement will taste the same, and be placed into identical packaging, and be randomly labelled (e.g., A, B, C). This will be done to avoid potential bias.

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.