Splenda: Effects on Blood Glucose Concentration, Appetite Scores and Subsequent Energy Intake
NCT ID: NCT05810337
Last Updated: 2023-04-12
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
51 participants
INTERVENTIONAL
2023-01-18
2023-03-13
Brief Summary
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Detailed Description
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Blood glucose measurements will be obtained through finger-pricking and appetite will be measured using self-reported visual analogue scores rating hunger, desire to eat, fullness and alertness for up to 3 hours after breakfast. Energy intake will be measured using a 24 hour food diary.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
BASIC_SCIENCE
TRIPLE
Study Groups
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Splenda drink
Drink containing 4.5g Splenda dissolved on 250ml water.
Splenda drink
4.5g Splenda containing 1% sucralose, 95% maltodextrin, dissolved in 250ml water and consumed with a high carbohydrate breakfast.
High carbohydrate breakfast
Meal consisting of 30g cereal with 100ml skimmed milk, 1.5 slices white toast with 12g margarine, providing 386kcal, 61.4g carbohydrate, 10.4g protein and 10.1g fat.
Maltodextrin drink
Drink containing 4.5g maltodextrin dissolved on 250ml water.
Maltodextrin drink
4.5g maltodextrin dissolved in 250ml water and consumed with a high carbohydrate breakfast.
High carbohydrate breakfast
Meal consisting of 30g cereal with 100ml skimmed milk, 1.5 slices white toast with 12g margarine, providing 386kcal, 61.4g carbohydrate, 10.4g protein and 10.1g fat.
Interventions
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Splenda drink
4.5g Splenda containing 1% sucralose, 95% maltodextrin, dissolved in 250ml water and consumed with a high carbohydrate breakfast.
Maltodextrin drink
4.5g maltodextrin dissolved in 250ml water and consumed with a high carbohydrate breakfast.
High carbohydrate breakfast
Meal consisting of 30g cereal with 100ml skimmed milk, 1.5 slices white toast with 12g margarine, providing 386kcal, 61.4g carbohydrate, 10.4g protein and 10.1g fat.
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
18 Years
64 Years
ALL
Yes
Sponsors
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King's College London
OTHER
Responsible Party
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Dr Christopher Corpe
Nutrition Sciences Lecturer, Principal investigator
Principal Investigators
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Christopher Corpe, Dr.
Role: PRINCIPAL_INVESTIGATOR
King's College London
Locations
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King's College London
London, , United Kingdom
Countries
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Other Identifiers
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KCLMScNutr2023
Identifier Type: -
Identifier Source: org_study_id
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