The Effect of Ingesting or Rinsing Sucrose and Sucralose on Self-control, Cognitive Performance, and Blood Glucose

NCT ID: NCT02075333

Last Updated: 2016-05-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

40 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-01-31

Study Completion Date

2014-08-31

Brief Summary

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The purpose of this study is to examine the effects of ingesting or mouth rinsing a sucrose (carbohydrate) versus a sucralose (carbohydrate-free) drink on self control, cognitive performance, and blood glucose level.

Detailed Description

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Conditions

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Self-control Cognitive Performance Blood Glucose Response

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

SINGLE

Participants

Study Groups

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Sucrose (50g)

A 381g blackcurrant drink (cordial and water) providing 50g of sucrose

Group Type ACTIVE_COMPARATOR

Ingestion of solution

Intervention Type DIETARY_SUPPLEMENT

Participants will ingest the solution

Rinising of solution

Intervention Type DIETARY_SUPPLEMENT

Participants rinse the solution in the oral cavity

Sucralose (0.92 g sugars)

A 381g blackcurrant drink (cordial and water) providing 0.92g of natural sugars

Group Type PLACEBO_COMPARATOR

Ingestion of solution

Intervention Type DIETARY_SUPPLEMENT

Participants will ingest the solution

Rinising of solution

Intervention Type DIETARY_SUPPLEMENT

Participants rinse the solution in the oral cavity

Interventions

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Ingestion of solution

Participants will ingest the solution

Intervention Type DIETARY_SUPPLEMENT

Rinising of solution

Participants rinse the solution in the oral cavity

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* BMI 18 - 29 kg/m2

Exclusion Criteria

* Dementia
* Depression
* Type 2 diabetes
* Phenylketonuria
* Intake of medication known to affect glucose metabolism
* Fasting blood glucose \> 7.8 mmol/L
Minimum Eligible Age

50 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Sugar Nutrition, UK

UNKNOWN

Sponsor Role collaborator

University of Leeds

OTHER

Sponsor Role lead

Responsible Party

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Prof Louise Dye

Chair of Nutrition and Behaviour

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Neil B Boyle

Role: PRINCIPAL_INVESTIGATOR

University of Leeds

Louise Dye

Role: STUDY_CHAIR

University of Leeds

Locations

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Human Appetite Research Unit (University of Leeds)

Leeds, , United Kingdom

Site Status

Countries

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United Kingdom

Other Identifiers

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SN - 0114

Identifier Type: -

Identifier Source: org_study_id

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