The Impact of Sucrose Ingestion During Exercise on Liver and Muscle Glycogen Concentration.
NCT ID: NCT02110836
Last Updated: 2015-08-07
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
COMPLETED
NA
14 participants
INTERVENTIONAL
2014-04-30
2015-04-30
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
The carbohydrates typically found in sports drinks are glucose and sometimes fructose. If glucose only is ingested during exercise, then the maximum rate at which can be absorbed from the intestine into the blood stream is \~1 g/min. However, if different sources of carbohydrate (fructose) are used, which are absorbed through a different pathway, absorption of carbohydrate can be up to \~1.8 g/min. With more carbohydrate available as a fuel, this translates into an improvement in performance.
Sucrose is a naturally occurring sugar that is made up of a single glucose and single fructose molecule. Therefore, theoretically, this can use the two different pathways of absorption and also maximise carbohydrate delivery. It is not yet known however, what impact this has on our liver and muscle glycogen stores during exercise. Therefore the aim of this study is to assess whether sucrose ingestion influences liver and muscle glycogen depletion during endurance exercise.
Related Clinical Trials
Explore similar clinical trials based on study characteristics and research focus.
The Impact of Sucrose Ingestion Post-Exercise on Liver and Muscle Glycogen Repletion.
NCT02344381
Carbohydrate Feeding Frequency, Muscle Glycogen and Exercise Capacity in Runners
NCT03749785
The Effect of Ingesting or Rinsing Sucrose and Sucralose on Self-control, Cognitive Performance, and Blood Glucose
NCT02075333
Steviol Glycoside for Use in Restoring Muscle Glycogen by Increasing the Rate of Glycogen Re-synthesis in Muscles
NCT02146183
Effect of Glycogen Replenishment on Time Trial Performance Following a Glycogen Lowering Exercise
NCT03682861
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
RANDOMIZED
CROSSOVER
BASIC_SCIENCE
TRIPLE
Study Groups
Review each arm or cohort in the study, along with the interventions and objectives associated with them.
Glucose ingestion
Glucose ingestion during exercise at a rate of 1.8 g/min.
Glucose ingestion
Glucose ingestion during exercise at 1.8 g/min
Sucrose ingestion
Sucrose ingestion during exercise at a rate of 1.8 g/min.
Sucrose ingestion
Sucrose ingestion during exercise at 1.8 g/min
Interventions
Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.
Glucose ingestion
Glucose ingestion during exercise at 1.8 g/min
Sucrose ingestion
Sucrose ingestion during exercise at 1.8 g/min
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
* Male
* 18 - 35 years of age
* Endurance trained cyclist/triathlete
* VO2 max ≥ 50 ml/kg/min
Exclusion Criteria
* Smoking
* Metabolic disorders
18 Years
35 Years
MALE
Yes
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
University of Newcastle Upon-Tyne
OTHER
Maastricht University
OTHER
Sugar Nutrition, UK
UNKNOWN
Javier Gonzalez, PhD
OTHER
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Javier Gonzalez, PhD
Research Fellow
Principal Investigators
Learn about the lead researchers overseeing the trial and their institutional affiliations.
Luc van Loon, PhD
Role: PRINCIPAL_INVESTIGATOR
Maastricht University
Locations
Explore where the study is taking place and check the recruitment status at each participating site.
Northumbria University
Newcastle upon Tyne, Tyne and Wear, United Kingdom
Countries
Review the countries where the study has at least one active or historical site.
References
Explore related publications, articles, or registry entries linked to this study.
Gonzalez JT, Fuchs CJ, Smith FE, Thelwall PE, Taylor R, Stevenson EJ, Trenell MI, Cermak NM, van Loon LJ. Ingestion of glucose or sucrose prevents liver but not muscle glycogen depletion during prolonged endurance-type exercise in trained cyclists. Am J Physiol Endocrinol Metab. 2015 Dec 15;309(12):E1032-9. doi: 10.1152/ajpendo.00376.2015. Epub 2015 Oct 20.
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
NUSUCA
Identifier Type: -
Identifier Source: org_study_id
More Related Trials
Additional clinical trials that may be relevant based on similarity analysis.