Galactose Mediated Glycogen Resynthesis

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

9 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-07-01

Study Completion Date

2020-05-01

Brief Summary

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This study will compare short-term post-exercise muscle glycogen synthesis following combined galactose-glucose, glucose alone or galactose alone ingestion.

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Detailed Description

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Lactose, the sugar contained within milk, consists of glucose and galactose. Post-exercise consumption of a carbohydrate mixture containing glucose with galactose has been shown to accelerate liver glycogen repletion as compared to glucose-only provision. However, the extent to which galactose-glucose combinations influence post-exercise muscle glycogen storage has yet to be determined.

Therefore, this study will investigate whether short-term muscle glycogen storage after strenuous endurance exercise is enhanced by combined galactose-glucose or glucose only ingestion as compared to the ingestion of galactose alone.

Conditions

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Exercise

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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Glucose alone

Participants will complete a glycogen depleting bout of exercise followed by the provision of glucose-alone over 4 hours of recovery before a subsequent bout of exercise.

Group Type EXPERIMENTAL

Glucose alone

Intervention Type OTHER

Young men or women will complete a glycogen depleting bout of exercise followed by the provision of glucose-alone over 4 hours of recovery before a subsequent bout of exercise.

Galactose alone

Participants will complete a glycogen depleting bout of exercise followed by the provision of galactose-alone over 4 hours of recovery before a subsequent bout of exercise.

Group Type EXPERIMENTAL

Galactose alone

Intervention Type OTHER

Young men or women will complete a glycogen depleting bout of exercise followed by the provision of galactose-alone over 4 hours of recovery before a subsequent bout of exercise.

Glucose and galactose

Participants will complete a glycogen depleting bout of exercise followed by the provision of glucose and galactose over 4 hours of recovery before a subsequent bout of exercise.

Group Type EXPERIMENTAL

Glucose and galactose

Intervention Type OTHER

Young men or women will complete a glycogen depleting bout of exercise followed by the provision of glucose and galactose over 4 hours of recovery before a subsequent bout of exercise.

Interventions

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Glucose alone

Young men or women will complete a glycogen depleting bout of exercise followed by the provision of glucose-alone over 4 hours of recovery before a subsequent bout of exercise.

Intervention Type OTHER

Galactose alone

Young men or women will complete a glycogen depleting bout of exercise followed by the provision of galactose-alone over 4 hours of recovery before a subsequent bout of exercise.

Intervention Type OTHER

Glucose and galactose

Young men or women will complete a glycogen depleting bout of exercise followed by the provision of glucose and galactose over 4 hours of recovery before a subsequent bout of exercise.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Body mass index in the range: 18.5 - 27.5 kg/m2
* Participates in endurance-based exercise (e.g. cycling, running, rowing) at least 3 times per week
* Aerobic fitness: VO2max \>45 ml/kg/min (men), \>40 ml/kg/min (women)

Exclusion Criteria

* Lidocaine allergy
* Current participation in another scientific/clinical study
* Bleeding disorder/s
* Current or recent smoker to include vaping (last 60 days)
* Vegan
* Existence of food intolerances
* Poor recent health as indicated in the general health questionnaire
* Engage in uncommon eating practices (e.g. sustained periods of fasting)
* Diagnosed with galactosemia

Minimum Eligible Age

18 Years

Maximum Eligible Age

45 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes