Exogenous Oxidation of Fructose-glucose Mixtures During Running

NCT ID: NCT03731065

Last Updated: 2019-12-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

9 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-10-14

Study Completion Date

2019-11-30

Brief Summary

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The aim of this study is to characterise exogenous carbohydrate oxidation rates during exercise, when ingesting glucose (polymers) only, compared to glucose-fructose mixtures, and glucose-fructose mixtures ingested in hydrogel form.

Detailed Description

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Conditions

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Exercise

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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Fructose-maltodextrin ingestion

Ingestion of fructose and maltodextrin (glucose polymers) at a rate of 90 g carbohydrate per hour during two hours of treadmill running at 60%VO2peak.

Group Type ACTIVE_COMPARATOR

Fructose-maltodextrin

Intervention Type DIETARY_SUPPLEMENT

Fructose plus maltodextrin in a ratio of 1:1.4, diluted in water to produce a 16% carbohydrate solution.

Fructose-maltodextrin hydrogel ingestion

Ingestion of fructose and maltodextrin (glucose polymers) encapsulated in alginate-pectin hydrogel, drinks at a rate of 90 g carbohydrate per hour during two hours of treadmill running at 60%VO2peak.

Group Type EXPERIMENTAL

Fructose-maltodextrin hydrogel

Intervention Type DIETARY_SUPPLEMENT

Fructose plus maltodextrin in a ratio of 1:1.4, encapsulated in an alginate-pectin hydrogel diluted in water to produce a 16% carbohydrate solution.

Glucose-maltodextrin ingestion

Ingestion of glucose and maltodextrin (glucose polymers) at a rate of 90 g carbohydrate per hour during two hours of treadmill running at 60%VO2peak.

Group Type ACTIVE_COMPARATOR

Glucose-maltodextrin

Intervention Type DIETARY_SUPPLEMENT

Glucose plus maltodextrin in a ratio of 1:1.4, diluted in water to produce a 16% carbohydrate solution.

Interventions

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Fructose-maltodextrin

Fructose plus maltodextrin in a ratio of 1:1.4, diluted in water to produce a 16% carbohydrate solution.

Intervention Type DIETARY_SUPPLEMENT

Fructose-maltodextrin hydrogel

Fructose plus maltodextrin in a ratio of 1:1.4, encapsulated in an alginate-pectin hydrogel diluted in water to produce a 16% carbohydrate solution.

Intervention Type DIETARY_SUPPLEMENT

Glucose-maltodextrin

Glucose plus maltodextrin in a ratio of 1:1.4, diluted in water to produce a 16% carbohydrate solution.

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* Maximal oxygen consumption \> 50 ml.kg-1.min-1
* \> 1 year training in endurance running or triathlon
* No current injury or injury within the last three months
* No history of cardiac or metabolic disease such as coronary heart disease or diabetes
* No current or history of gastrointestinal issues
* Successful completion of the physical activity readiness questionnaire (PAR-Q)

Exclusion Criteria

* Female
* Untrained in endurance running
* Current injury or injury within the past three months
* History of cardiac or metabolic disease such as coronary heart disease or diabetes
* History of or current gastrointestinal issues such as irritable bowel syndrome
* Unable to replicate diet and training for 3 and 5 days respectively prior to each experimental visit.
Minimum Eligible Age

18 Years

Maximum Eligible Age

50 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

Yes

Sponsors

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University of Birmingham

OTHER

Sponsor Role collaborator

University of Bath

OTHER

Sponsor Role lead

Responsible Party

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Javier Gonzalez

Associate Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Department for Health, University of Bath

Bath, , United Kingdom

Site Status

Countries

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United Kingdom

Other Identifiers

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MSES 17/18-001

Identifier Type: -

Identifier Source: org_study_id