Acute Metabolic and Endocrine Responses of Glucose and Fructose in Healthy Young Subjects
NCT ID: NCT02590913
Last Updated: 2015-10-29
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
20 participants
INTERVENTIONAL
2015-03-31
2015-06-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
CROSSOVER
PREVENTION
TRIPLE
Study Groups
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group fructose
Volunteer was randomized into either group fructose or glucose
fructose
75g fructose is dissolved in 300 ml water.After overnight fasting, 300ml of solution at 0830 within 5 minutes is taken by volunteers
glucose
75g glucose is dissolved in 300 ml water.After overnight fasting, 300ml of solution at 0830 within 5 minutes is taken by volunteers
group glucose
After one-week washout period, volunteer was crossed over for either group glucose or fructose.
fructose
75g fructose is dissolved in 300 ml water.After overnight fasting, 300ml of solution at 0830 within 5 minutes is taken by volunteers
glucose
75g glucose is dissolved in 300 ml water.After overnight fasting, 300ml of solution at 0830 within 5 minutes is taken by volunteers
Interventions
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fructose
75g fructose is dissolved in 300 ml water.After overnight fasting, 300ml of solution at 0830 within 5 minutes is taken by volunteers
glucose
75g glucose is dissolved in 300 ml water.After overnight fasting, 300ml of solution at 0830 within 5 minutes is taken by volunteers
Eligibility Criteria
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Exclusion Criteria
* Subjects taking any drugs, botanicals, or nutraceutical known to influence blood pressure also were rejected either.
19 Years
39 Years
ALL
Yes
Sponsors
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Zhejiang University
OTHER
Responsible Party
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Duo li
Professor
Principal Investigators
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Duo Li, Doctor
Role: STUDY_DIRECTOR
College of Biosystem Engineering & Food Science, Zhejiang University
Locations
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Zhejiang university
Hangzhou, Zhejiang, China
Countries
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References
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Fulgoni V 3rd. High-fructose corn syrup: everything you wanted to know, but were afraid to ask. Am J Clin Nutr. 2008 Dec;88(6):1715S. doi: 10.3945/ajcn.2008.25825A.
Le MT, Frye RF, Rivard CJ, Cheng J, McFann KK, Segal MS, Johnson RJ, Johnson JA. Effects of high-fructose corn syrup and sucrose on the pharmacokinetics of fructose and acute metabolic and hemodynamic responses in healthy subjects. Metabolism. 2012 May;61(5):641-51. doi: 10.1016/j.metabol.2011.09.013. Epub 2011 Dec 5.
Other Identifiers
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Zhejiang University
Identifier Type: -
Identifier Source: org_study_id
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