Effects of Glucose-fructose Drinks During Training on Lactate Transport

NCT ID: NCT01610986

Last Updated: 2014-06-04

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

17 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-05-31

Study Completion Date

2014-03-31

Brief Summary

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The purpose of this study is to determine whether glucose-fructose intake during training increases lactate transport and oxidation and improve endurance performance.

Detailed Description

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The study will enroll 24 healthy male volunteers. After baseline assessment of lactate transport and endurance performance, subjects will be randomized to either a 3-week intervention arm in which they will train with glucose-fructose intake during training, or to a control arm (water during training). After this 3-week intervention, lactate transport and endurance performance will be assessed again.

Conditions

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Normal Physiology on Healthy Subjects

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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Glucose-fructose

Participants will take glucose-fructose drinks during training sessions

Group Type EXPERIMENTAL

Glucose-fructose

Intervention Type DIETARY_SUPPLEMENT

0.8 g/h glucose and 0.5 g/h fructose during training

Water

Participants will take only water during training sessions

Group Type EXPERIMENTAL

Water

Intervention Type DIETARY_SUPPLEMENT

Only water intake during training

Interventions

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Glucose-fructose

0.8 g/h glucose and 0.5 g/h fructose during training

Intervention Type DIETARY_SUPPLEMENT

Water

Only water intake during training

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* healthy
* age between 18 and 30 years
* sedentary
* BMI between 19 and 25
* blood pressure lower than 140/90 mmHg

Exclusion Criteria

* smoking
* consumption of more than 10g alcohol per day
* cardiovascular history
* electrographic abnormalities at rest
* consumption of more than one can of soda per day or more than 60g sugars per day
* any current drug treatment
* consumption of drugs or illicit substances
* diabetes mellitus
* vegetarian
* food intolerance
* blood donation or participation to another study \<3 months before study inclusion
Minimum Eligible Age

18 Years

Maximum Eligible Age

30 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

Yes

Sponsors

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Centre Hospitalier Universitaire Vaudois

OTHER

Sponsor Role collaborator

University of Lausanne

OTHER

Sponsor Role lead

Responsible Party

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Luc Tappy, MD

Professor of Physiology

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Luc Tappy, Pr

Role: PRINCIPAL_INVESTIGATOR

University of Lausanne

Locations

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University of Lausanne

Lausanne, Canton of Vaud, Switzerland

Site Status

Countries

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Switzerland

References

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Lecoultre V, Benoit R, Carrel G, Schutz Y, Millet GP, Tappy L, Schneiter P. Fructose and glucose co-ingestion during prolonged exercise increases lactate and glucose fluxes and oxidation compared with an equimolar intake of glucose. Am J Clin Nutr. 2010 Nov;92(5):1071-9. doi: 10.3945/ajcn.2010.29566. Epub 2010 Sep 8.

Reference Type BACKGROUND
PMID: 20826630 (View on PubMed)

Other Identifiers

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251/11

Identifier Type: -

Identifier Source: org_study_id

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