Berry Components and Blood Sugar & Fat Metabolism

NCT ID: NCT03458858

Last Updated: 2019-05-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

36 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-02-13

Study Completion Date

2018-06-28

Brief Summary

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The primary objective of this study is to determine which components of berries improve glucose metabolism and increase fat oxidation in humans.

Detailed Description

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The aim of this study is to improve understanding of how diet can regulate glucose metabolism and fuel use. Previous human and animal studies have demonstrated that berries can improve gluco-regulation and increase fat oxidation. The aim of this study is to determine which component of berries is conveying this health benefit.

Conditions

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Healthy Volunteers

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

OTHER

Blinding Strategy

DOUBLE

Investigators Outcome Assessors

Study Groups

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Mixed Berry Diet

Participants will receive between 400 to 800 grams of mixed berries daily, as a proportion of their daily caloric intake added to their base diet. The base diet will be prepared using traditional American foods with a macronutrient composition representative of a typical American diet.

Group Type OTHER

Mixed Berry Diet

Intervention Type OTHER

Mixed Berry Treatment

Carbohydrate Control Jello

Participants will receive between 400 to 800 grams of strawberry jello daily, as a proportion of their daily caloric intake added to their base diet. The jello will be matched to the mixed berries in both total carbohydrate level and gram quantity. The base diet will be prepared using traditional American foods with a macronutrient composition representative of a typical American diet.

Group Type OTHER

Carbohydrate Control Jello

Intervention Type OTHER

Carbohydrate Control

Fiber Enriched Jello

Participants will receive between 400 to 800 grams of fiber enriched strawberry jello daily, as a proportion of their daily caloric intake added to their base diet. The jello will be matched to the mixed berries in both total carbohydrate level and fiber content, and in the same gram quantity. The base diet will be prepared using traditional American foods with a macronutrient composition representative of a typical American diet.

Group Type OTHER

Fiber Enriched Jello

Intervention Type OTHER

Fiber Control

Low Fiber Mixed Berry Juice

Participants will receive 1 liter per day of low fiber mixed berry juice added to their base diet. The juice will be squeezed from the mixed berries, then filtered. The sugar level of the juice will match that of the mixed berries. The base diet will be prepared using traditional American foods with a macronutrient composition representative of a typical American diet.

Group Type OTHER

Low Fiber Mixed Berry Juice

Intervention Type OTHER

Anthocyanin Control

Interventions

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Mixed Berry Diet

Mixed Berry Treatment

Intervention Type OTHER

Carbohydrate Control Jello

Carbohydrate Control

Intervention Type OTHER

Fiber Enriched Jello

Fiber Control

Intervention Type OTHER

Low Fiber Mixed Berry Juice

Anthocyanin Control

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Healthy non-smoker
* able to understand consent

Exclusion Criteria

* Body Mass Index less than 25 kg/m2
* pregnant, lactating, having given birth in the past year
* allergy to berries
* blood glucose greater than 125 mg/dL
* history of bariatric surgery or nutrient malabsorption disease
* diagnosis or treatment of cancer in past three years
* type 2 diabetes requiring the use of diabetes pills, insulin, or non-insulin shots
Minimum Eligible Age

21 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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USDA Beltsville Human Nutrition Research Center

FED

Sponsor Role lead

Responsible Party

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Janet Novotny

Research Physiologist

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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USDA-ARS Beltsville Human Nutrition Research Center

Beltsville, Maryland, United States

Site Status

Countries

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United States

Other Identifiers

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HS59

Identifier Type: -

Identifier Source: org_study_id

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