Effects of Faba Bean Fractions as Ingredients in Novel Food Products on Glycemia, Appetite and Metabolic Control

NCT ID: NCT02666586

Last Updated: 2023-01-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-01-31

Study Completion Date

2017-10-21

Brief Summary

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To describe the effect and mechanisms of action faba bean powder and fractions (protein, starch and fiber) on glucose and insulin homeostasis, food intake, satiety and metabolic regulation in young adults (18 to 30 years).

Detailed Description

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The overall objective is to describe the effect and mechanisms of action of faba bean powder and fractions (protein, starch and fiber) on glucose and insulin homeostasis, food intake, satiety and metabolic regulation in young adults (18 to 30 years). The specific objectives are to test the acute effects of different faba bean ingredient smoothie on: 1) post-prandial blood glucose, appetite, satiety hormone and insulin for 200 minutes, and 2) food intake 120 minutes following consumption of the faba bean smoothie. Two short-term acute studies will be conducted to meet these objectives. Both acute studies will follow a randomized, double blinded, balanced, repeated measures design and the same protocol; except one will have an ad libitum pizza meal (study 1), while the other will have a fixed pizza meal (study 2) at 120 minutes. Half the participants will have blood drawn by IV and the other half will be finger prick.

Conditions

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Faba Bean Post-prandial Blood Glucose Appetite Satiety Hormones Insulin

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

DOUBLE

Participants Caregivers

Study Groups

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Control smoothie

Control smoothie with 32 g corn maltodextrin without added faba bean fractions.

Group Type PLACEBO_COMPARATOR

Faba bean powder smoothie

Intervention Type OTHER

Breakfast smoothie with 32 g whole faba bean powder (300g).

Faba bean protein concentrate smoothie

Intervention Type OTHER

Breakfast smoothie with 32 g faba bean protein concentrate.

Faba bean starch smoothie

Intervention Type OTHER

Breakfast smoothie with 33 g faba bean starch.

Faba bean protein isolate smoothie

Intervention Type OTHER

Breakfast smoothie with 32 g faba bean protein isolate.

Faba Bean powder smoothie

Breakfast smoothie with 32 g whole faba bean powder.

Group Type EXPERIMENTAL

Faba bean protein concentrate smoothie

Intervention Type OTHER

Breakfast smoothie with 32 g faba bean protein concentrate.

Faba bean starch smoothie

Intervention Type OTHER

Breakfast smoothie with 33 g faba bean starch.

Faba bean protein isolate smoothie

Intervention Type OTHER

Breakfast smoothie with 32 g faba bean protein isolate.

Non-pulse smoothie smoothie

Intervention Type OTHER

Control smoothie with 32 g corn maltodextrin without added faba bean fractions.

Faba bean protein concentrate smoothie

Breakfast smoothie with 32 g faba bean protein concentrate.

Group Type EXPERIMENTAL

Faba bean powder smoothie

Intervention Type OTHER

Breakfast smoothie with 32 g whole faba bean powder (300g).

Faba bean starch smoothie

Intervention Type OTHER

Breakfast smoothie with 33 g faba bean starch.

Faba bean protein isolate smoothie

Intervention Type OTHER

Breakfast smoothie with 32 g faba bean protein isolate.

Non-pulse smoothie smoothie

Intervention Type OTHER

Control smoothie with 32 g corn maltodextrin without added faba bean fractions.

Faba bean starch smoothie

Breakfast smoothie with 33 g faba bean starch.

Group Type EXPERIMENTAL

Faba bean powder smoothie

Intervention Type OTHER

Breakfast smoothie with 32 g whole faba bean powder (300g).

Faba bean protein concentrate smoothie

Intervention Type OTHER

Breakfast smoothie with 32 g faba bean protein concentrate.

Faba bean protein isolate smoothie

Intervention Type OTHER

Breakfast smoothie with 32 g faba bean protein isolate.

Non-pulse smoothie smoothie

Intervention Type OTHER

Control smoothie with 32 g corn maltodextrin without added faba bean fractions.

Faba bean protein isolate smoothie

Breakfast smoothie with 32 g faba bean protein isolate.

Group Type EXPERIMENTAL

Faba bean powder smoothie

Intervention Type OTHER

Breakfast smoothie with 32 g whole faba bean powder (300g).

Faba bean protein concentrate smoothie

Intervention Type OTHER

Breakfast smoothie with 32 g faba bean protein concentrate.

Faba bean starch smoothie

Intervention Type OTHER

Breakfast smoothie with 33 g faba bean starch.

Non-pulse smoothie smoothie

Intervention Type OTHER

Control smoothie with 32 g corn maltodextrin without added faba bean fractions.

Interventions

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Faba bean powder smoothie

Breakfast smoothie with 32 g whole faba bean powder (300g).

Intervention Type OTHER

Faba bean protein concentrate smoothie

Breakfast smoothie with 32 g faba bean protein concentrate.

Intervention Type OTHER

Faba bean starch smoothie

Breakfast smoothie with 33 g faba bean starch.

Intervention Type OTHER

Faba bean protein isolate smoothie

Breakfast smoothie with 32 g faba bean protein isolate.

Intervention Type OTHER

Non-pulse smoothie smoothie

Control smoothie with 32 g corn maltodextrin without added faba bean fractions.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* healthy
* non-smoking males
* aged 20-30 years (min/max age)
* a body mass index between 20 and 25 kg/m2 (the range generally accepted as ideal/healthy by Health and Welfare Canada)

Exclusion Criteria

* individuals diagnosed with diabetes
* those on medication
* breakfast skippers
* on an energy restricted diet
* this study excludes females because appetite and blood glucose during the female menstruation cycle changes due to fluctuations in hormones
Minimum Eligible Age

20 Years

Maximum Eligible Age

30 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

Yes

Sponsors

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University of Manitoba

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Richardson Centre for Functional Foods and Nutraceuticals

Winnipeg, Manitoba, Canada

Site Status

Countries

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Canada

Other Identifiers

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B2015:110

Identifier Type: -

Identifier Source: org_study_id

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