Acute Effects of Instant Coffee in Capsule vs Beverage Form on Plasma Metabolites

NCT ID: NCT07051291

Last Updated: 2025-07-04

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

15 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-09-22

Study Completion Date

2022-10-10

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

This study is designed to evaluate the acute effect of consuming a cup of instant coffee on circulating metabolites and to evaluate whether ingestion of instant coffee in the form of a capsule has a similar effect on circulating metabolites as compared to the conventionally prepared beverage.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Coffee

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Participants will receive both interventions (instant coffee capsule and instant coffee beverage) in a randomized order across two visits.
Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Instant coffee capsule/ coffee beverage

Group Type EXPERIMENTAL

Instant Coffee Capsule

Intervention Type DIETARY_SUPPLEMENT

Participants received 1.7 grams of instant coffee in the form of three capsules. 200 mL of plain water was provided to participants to swallow the three capsules.

Instant Coffee Beverage

Intervention Type DIETARY_SUPPLEMENT

Dissolved 1.7 grams of instant coffee in 200 mL of hot water to make a coffee beverage.

Instant coffee beverage/ coffee capsule

Group Type EXPERIMENTAL

Instant Coffee Capsule

Intervention Type DIETARY_SUPPLEMENT

Participants received 1.7 grams of instant coffee in the form of three capsules. 200 mL of plain water was provided to participants to swallow the three capsules.

Instant Coffee Beverage

Intervention Type DIETARY_SUPPLEMENT

Dissolved 1.7 grams of instant coffee in 200 mL of hot water to make a coffee beverage.

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Instant Coffee Capsule

Participants received 1.7 grams of instant coffee in the form of three capsules. 200 mL of plain water was provided to participants to swallow the three capsules.

Intervention Type DIETARY_SUPPLEMENT

Instant Coffee Beverage

Dissolved 1.7 grams of instant coffee in 200 mL of hot water to make a coffee beverage.

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Exclusion Criteria

* Pregnant or breastfeeding
* Certain medications including Zanaflex, Sirasalud, Ketanest S, Spravato and Ephedrine Sulfate
* Any pre-existing medical conditions, depression, anxiety, caffeine/lactose intolerant, fear of needles and/or blood disorders, allergy to coffee or bovine capsules
* Existing dietary restrictions which makes them unable to consume non-halal certified bovine gelatin (the capsule encasing the coffee powder)
* Recent history of major surgical operations in the past year
* Past or current user of oral/systemic hormone treatment or therapies
* Taken antibiotics in the last 3 months
* Taking nutritional supplements (that contains coffee/tea-related compounds naturally found in other plants)
* Not willing to travel to the University for the study
* Unable to commit to completing both study visits
Minimum Eligible Age

21 Years

Maximum Eligible Age

64 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

National University of Singapore

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Seow Wei Jie

Assistant Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Saw Swee Hock School of Public Health, National University of Singapore

Singapore, , Singapore

Site Status

Countries

Review the countries where the study has at least one active or historical site.

Singapore

Provided Documents

Download supplemental materials such as informed consent forms, study protocols, or participant manuals.

Document Type: Study Protocol and Statistical Analysis Plan

View Document

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

NUS-IRB-2021-464

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

Speed of Glucose Absorption
NCT06375577 COMPLETED NA
Effect of Umami Exposure on MSG Induced-satiation
NCT06725615 NOT_YET_RECRUITING NA