Effects of Aerobic Versus Resistance Training in Post Percutaneous Coronary Intervention Obese Patients

NCT ID: NCT06308276

Last Updated: 2024-07-23

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 50 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2024-03-01
• Study Completion Date: 2024-06-15

Brief Summary

The randomized clinical trial (RCT) endeavors to enroll 50 participants, divided equally into aerobic exercise and resistance exercise groups. The study employs rigorous tools such as blood pressure measurement, SF-36 questionnaire, and the Six-Minute Walk Test (6MWT) to assess VO2max.

Detailed Description

The randomized clinical trial (RCT) endeavors to enroll 50 participants, divided equally into aerobic exercise and resistance exercise groups. The non-probability convenient sampling technique, followed by random allocation using a lottery method, ensures a diverse yet unbiased sample. Will be conducted at the Sialkot Medical and Physiotherapy Centre, the inclusion criteria will focus on post-PCI patients aged 40-60, presenting with a BMI of 30 or higher. The study employs rigorous tools such as blood pressure measurement, SF-36 questionnaire, and the Six-Minute Walk Test (6MWT) to assess VO2max. The aerobic exercise group undergoes sessions three times a week, progressively increasing in duration and intensity, emphasizing activities like brisk walking and cycling. The resistance exercise group follows a similar schedule, engaging in full-body resistance exercises targeting major muscle groups. Both groups undergo assessments using cardiopulmonary exercise testing (CPET) to determine exercise tolerance accurately.

Conditions

Cardiovascular Diseases

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: TREATMENT
• Blinding Strategy: SINGLE

Study Groups

Group A

Brisk walking, jogging, cycling, or low-impact aerobics

Group Type: ACTIVE_COMPARATOR

Aerobic Training

Intervention Type: OTHER

Aerobic Training: Brisk walking, jogging, cycling, or low-impact aerobics

Group B

Full body resistance exercise targeting major muscle groups, including squats, lunges, chest presses, rows, and core exercises

Group Type: ACTIVE_COMPARATOR

Resistance Training

Intervention Type: OTHER

Resistance Training: Full body resistance exercise targeting major muscle groups, including squats, lunges, chest presses, rows, and core exercises

Interventions

Aerobic Training

Aerobic Training: Brisk walking, jogging, cycling, or low-impact aerobics

Intervention Type: OTHER

Resistance Training

Resistance Training: Full body resistance exercise targeting major muscle groups, including squats, lunges, chest presses, rows, and core exercises

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• Age: Participants must be between 40 and 60 years old.
• Gender: Male and female both.
• Cardiovascular Status: Post Percutaneous Coronary Intervention (PCI) patients with a documented history of coronary artery disease
• Participants who are at least three months post PCI to ensure stabilization of their cardiovascular condition.
• Obesity: Participants must have a Body Mass Index (BMI) equal to or greater than 30 kg/m², indicating obesity.
• Health Status: Participants should be in stable health condition to participate in moderate physical activities.
• Willingness to Participate: Participants must provide informed consent and be willing to comply with the study protocol, including attending scheduled exercise sessions and follow-up assessments.
• Participants capable of engaging in either aerobic or resistance training, were assessed by a physical activity readiness questionnaire (PAR-Q).

Exclusion Criteria

• Participants with severe physical limitations, disabilities, or musculoskeletal disorders that would prevent them from engaging in aerobic and resistance exercises.
• Individuals with a history of substance abuse or current substance abuse issues that might interfere with their ability to participate or adhere to the study protocol.
• Patients with Neurological diseases
• Patients with severe or unstable heart conditions, recent heart attack, or heart failure

• Minimum Eligible Age: 40 Years
• Maximum Eligible Age: 60 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Riphah International University

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

Muhammad Faizan Hamid, MS-CPPT

Role: PRINCIPAL_INVESTIGATOR

Riphah International University

Locations

Sialkot Medical and Physiotherapy Center

Sialkot, Punjab Province, Pakistan

Countries

Pakistan

Other Identifiers

REC/RCR&AHS/23/0363

Identifier Type: -

Identifier Source: org_study_id