Resistance Training in Adults With Obesity

NCT ID: NCT05092061

Last Updated: 2022-05-26

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 31 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2021-10-14
• Study Completion Date: 2022-02-28

Brief Summary

The purpose of this project is two-fold: (1) to assess if two different resistance training protocols elicit different responses in the acute phase and (2) to assess if the same two different protocols will elicit different long-term responses on muscular strength, body composition and cardiometabolic health. The project will include 30 adults with obesity (defined as BMI ≥ 30 or abdominal obesity according to the International Diabetes Federation). In the acute phase blood lactate, heart rate, enjoyment and perceived exertion will be assessed after the two resistance training protocols. In addition, the mean 24-h blood glucose concentration after exercise will be compared between the two protocols.

For the long-term effects blood markers of cardiometabolic health, blood pressure, body composition, objectively measured physical activity and physical fitness will be assessed before and after the intervention. Also, perceived health-related quality of life will be assessed before and after the intervention.

Conditions

Overweight and Obesity

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: PREVENTION
• Blinding Strategy: NONE

Study Groups

Moderate-repetition resistance training

The participants will undergo a full-body resistance training protocol with moderate repetitions (6-12), moderate load (70-85% of 1RM), and moderate rest between sets (60-90s). Training will be undertaken three times per week.

Group Type: EXPERIMENTAL

Moderate-repetition resistance training

Intervention Type: OTHER

Will undertake resistance training with moderate loads, and moderate repetitions 3 times per week for 7 weeks.

High-repetition resistance training

The participants will undergo a full-body resistance training protocol with high repetitions (15+), low load (\<60% of 1RM), and short rest between sets (30s). Training will be undertaken three times per week.

Group Type: EXPERIMENTAL

High-repetition resistance training

Intervention Type: OTHER

Will undertake resistance training with low loads, and high repetitions 3 times per week for 7 weeks.

Interventions

Moderate-repetition resistance training

Will undertake resistance training with moderate loads, and moderate repetitions 3 times per week for 7 weeks.

Intervention Type: OTHER

High-repetition resistance training

Will undertake resistance training with low loads, and high repetitions 3 times per week for 7 weeks.

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• Obesity (BMI ≥ 30) or
• Central obesity (defined according to the International Diabetes Federation).

Exclusion Criteria

• Unstable angina
• recent cardiac infarction (last 4 weeks)
• uncompensated heart failure
• severe valvular illness
• pulmonary disease
• uncontrolled hypertension
• kidney failure
• orthopaedic/neurological limitations
• cardiomyopathy
• planned operations during the research period
• participation in a parallel study

• Minimum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

Norwegian University of Science and Technology

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

Øystein Risa

Role: STUDY_DIRECTOR

Norwegian University of Science and Technology

Locations

Department of Circulation and Medical Imaging

Trondheim, , Norway

Countries

Norway

Other Identifiers

246888

Identifier Type: -

Identifier Source: org_study_id