Study of the Long-term Effects of Exercise on Heath Indicators in Older People

NCT ID: NCT01874132

Last Updated: 2017-05-08

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 66 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2011-05-31
• Study Completion Date: 2014-09-30

Brief Summary

Cardiovascular diseases (CVD) represent the most frequent cause of death among the elderly population. Hypertension, unfavorable lipid profile, obesity and physical inactivity are among the main risk factors for CVD. In contrast, mortality from CVD is inversely related to levels of physical activity, and is lower in individuals who exercise and have higher functional fitness levels. Thus, the Centers for Disease Control and Prevention, the American College of Sports Medicine, and the American Heart Association have recommended 20-30 min of moderate-to-vigorous aerobic training for the elderly, preferably every day or at least 3 days a week in the case of vigorous exercise.The same organizations also suggest the inclusion of resistance training in order to improve functional fitness. Therefore, the purpose of this study was to compare different exercise modalities in long-term changes of CVD risk factors and physical fitness among older adults.

Conditions

Hypertension With Complications and Secondary Hypertension; Overweight and Obesity; Lipid Metabolism Disorders; Sarcopenia; Osteoporosis; Personal Satisfaction

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: PREVENTION
• Blinding Strategy: SINGLE

Study Groups

Aerobic exercise training

Dose response

Group Type: EXPERIMENTAL

Exercise training

Intervention Type: BEHAVIORAL

Both training programs were of moderate-to-vigorous intensity, three days per week for nine months.

Aerobic and resistance exercise training

Dose response

Group Type: EXPERIMENTAL

Exercise training

Intervention Type: BEHAVIORAL

Both training programs were of moderate-to-vigorous intensity, three days per week for nine months.

Control

Non-exercising control group

Group Type: NO_INTERVENTION

No interventions assigned to this group

Interventions

Exercise training

Both training programs were of moderate-to-vigorous intensity, three days per week for nine months.

Intervention Type: BEHAVIORAL

Other Intervention Names

Aerobic training; resistance training; Combined training; multicomponent training

Eligibility Criteria

Inclusion Criteria

• Older adults living independently;
• medical approval.

Exclusion Criteria

• Non-smokers;
• Non-morbidly obese;
• No history of severe hypertension;
• No history of falls;
• No orthopaedic, neurological, pulmonary, or cardiac problems.

• Minimum Eligible Age: 65 Years
• Maximum Eligible Age: 79 Years
• Eligible Sex: MALE
• Accepts Healthy Volunteers: Yes

Sponsors

University of Trás-os-Montes and Alto Douro

OTHER

Sponsor Role: lead

Responsible Party

Nelson Joaquim Fortuna de Sousa

Professor

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Nelson Sousa, PhD

Role: PRINCIPAL_INVESTIGATOR

Research Center in Sport Sciences, Health Sciences and Human Development; University of Trás-os-Montes e Alto Douro

José Oliveira, PhD

Role: STUDY_DIRECTOR

Research Center in Physical Activity, Health and Leisure; Sport Faculty, University of Porto

Romeu Mendes, MD

Role: STUDY_CHAIR

University of Trás-os-Montes and Alto Douro

Locations

Maia City Council facilities

Maia, , Portugal

Countries

Portugal

References

Sousa N, Mendes R, Oliveira J. Response to Drs. Safer and Safer. J Am Geriatr Soc. 2014 Mar;62(3):590-1. doi: 10.1111/jgs.12712. No abstract available.

Reference Type: BACKGROUND

PMID: 24628645 (View on PubMed)

Sousa N, Mendes R, Abrantes C, Sampaio J, Oliveira J. Long-term effects of aerobic training versus combined aerobic and resistance training in modifying cardiovascular disease risk factors in healthy elderly men. Geriatr Gerontol Int. 2013 Oct;13(4):928-35. doi: 10.1111/ggi.12033. Epub 2013 Feb 26.

Reference Type: RESULT

PMID: 23441809 (View on PubMed)

Sousa N, Mendes R, Abrantes C, Sampaio J, Oliveira J. A randomized 9-month study of blood pressure and body fat responses to aerobic training versus combined aerobic and resistance training in older men. Exp Gerontol. 2013 Aug;48(8):727-33. doi: 10.1016/j.exger.2013.04.008. Epub 2013 Apr 26.

Reference Type: RESULT

PMID: 23628502 (View on PubMed)

Sousa N, Mendes R, Abrantes C, Sampaio J, Oliveira J. Is once-weekly resistance training enough to prevent sarcopenia? J Am Geriatr Soc. 2013 Aug;61(8):1423-4. doi: 10.1111/jgs.12387. No abstract available.

Reference Type: RESULT

PMID: 23937497 (View on PubMed)

Sousa N, Mendes R, Abrantes C, Sampaio J, Oliveira J. Effectiveness of combined exercise training to improve functional fitness in older adults: A randomized controlled trial. Geriatr Gerontol Int. 2014 Oct;14(4):892-8. doi: 10.1111/ggi.12188. Epub 2014 Apr 30.

Reference Type: RESULT

PMID: 24779956 (View on PubMed)

Sousa N, Mendes R, Abrantes C, Sampaio J, Oliveira J. A randomized study on lipids response to different exercise programs in overweight older men. Int J Sports Med. 2014 Dec;35(13):1106-11. doi: 10.1055/s-0034-1374639. Epub 2014 Jul 10.

Reference Type: RESULT

PMID: 25009971 (View on PubMed)

Sousa N, Mendes R, Silva A, Oliveira J. Combined exercise is more effective than aerobic exercise in the improvement of fall risk factors: a randomized controlled trial in community-dwelling older men. Clin Rehabil. 2017 Apr;31(4):478-486. doi: 10.1177/0269215516655857. Epub 2016 Jul 10.

Reference Type: RESULT

PMID: 27353246 (View on PubMed)

Other Identifiers

CVD-2009-EX

Identifier Type: -

Identifier Source: org_study_id