HIT in the Healthy Elderly Population

NCT ID: NCT02167191

Last Updated: 2015-10-01

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 24 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2014-02-28
• Study Completion Date: 2014-08-31

Brief Summary

It is widely known that exercise improves general fitness and that fitter patients recover more easily from illness and surgery. Conversely, unfit patients have a significantly higher morbidity and mortality after surgery and a longer inpatient stay. This will become increasingly important in an aging population as baseline fitness generally declines with age.

One method of improving cardiovascular fitness is by using low intensity endurance training programmes, a disadvantage of these it that they can take several months to show improvement. High intensity interval training (HIT) programmes that use short episodes of high intensity exercise have also been shown to improve fitness. These HIT programmes have also shown improvement in functional capacity and quality of life in patients with chronic disease. An advantage of HIT is that improvements in fitness may occur in a shorter time than traditional endurance training. It is also known that HIT can give superior gains over endurance training.

The primary aim of this study is to determine whether an improvement in aerobic fitness, as judged by a 2ml/kg/min increase in VO2peak, can be achieved within 31 days via a HIT programme, in a group of healthy elderly volunteers.

As a secondary aim we will assess whether this programme would be acceptable to the group studied, through determination of subject compliance and adherence to the training programme.

Conditions

Interval Training; Pre Operative Exercise; Prehabilitation; Elderly

Study Design

• Allocation Method: NA
• Intervention Model: SINGLE_GROUP
• Primary Study Purpose: BASIC_SCIENCE
• Blinding Strategy: NONE

Study Groups

HIT

High intensity interval training sessions on an cycle ergometer

Group Type: EXPERIMENTAL

HIT

Intervention Type: BEHAVIORAL

12 sessions of HIT exercise in 31 days on a stationary cycle ergometer

Interventions

HIT

12 sessions of HIT exercise in 31 days on a stationary cycle ergometer

Intervention Type: BEHAVIORAL

Eligibility Criteria

Inclusion Criteria

• Good health
• Male and female
• 60 -75 years old

Exclusion Criteria

• Uncontrolled hypertension (BP > 140/100)
• Angina
• Heart failure (NYHA class III/IV)
• Cardiac arrthymias
• Right to left cardiac shunt
• Recent cardiac event
• Previous stroke/TIA
• Aneurysm (large vessel or intracranial)
• Severe respiratory disease including pulmonary hypertension
• COPD/asthma with an FEV1 less than 1.5 l
• Inclusion into any other research study in the last three months which involved: taking a drug; being paid a disturbance allowance; having an invasive procedure or exposure to ionising radiation

• Minimum Eligible Age: 60 Years
• Maximum Eligible Age: 75 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

University of Nottingham

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Locations

University of Nottingham

Derby, Derbyshire, United Kingdom

Countries

United Kingdom

Other Identifiers

HIT

Identifier Type: -

Identifier Source: org_study_id