Effects of Exercise-intensity on Physiological Adaptations in Overweight and Obese

NCT ID: NCT01453972

Last Updated: 2016-08-02

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2011-10-31

Study Completion Date

2012-12-31

Brief Summary

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The main purpose of our study is to examine the physiological adaptations in oxygen transport chain for high-intensity exercise and moderate exercise in overweight and obese humans. The main goals are:

1. To investigate the most effective short-and long-interval training in terms of VO2max, pulmonary diffusion, cardiac output, endothelial function and mitochondrial function.
2. How these physiological adaptations affect the aerobic endurance and performance, and how this training can reduce the risk of cardiovascular diseases related to overweight and obesity.

Detailed Description

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Conditions

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Overweight Obesity

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Long distanse moderate training

40 minutes moderate treadmill running

Group Type EXPERIMENTAL

Long distanse moderate training

Intervention Type BEHAVIORAL

Moderate exercise

Long interval training

4x4min interval treadmill running

Group Type EXPERIMENTAL

Long interval training

Intervention Type BEHAVIORAL

High-intensity exercise, long duration

Short interval training

10x1min interval treadmill running

Group Type EXPERIMENTAL

Short interval training

Intervention Type BEHAVIORAL

High intensity exercise, short duration

Interventions

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Long distanse moderate training

Moderate exercise

Intervention Type BEHAVIORAL

Long interval training

High-intensity exercise, long duration

Intervention Type BEHAVIORAL

Short interval training

High intensity exercise, short duration

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* BMI \> 25
Minimum Eligible Age

18 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Norwegian University of Science and Technology

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Øivind Rognmo, PhD

Role: PRINCIPAL_INVESTIGATOR

Norwegian University of Science and Technology

Locations

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Medical Faculty, Norwegian University of Science and Technology

Trondheim, Sør-Trøndelag, Norway

Site Status

Countries

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Norway

References

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Baekkerud FH, Solberg F, Leinan IM, Wisloff U, Karlsen T, Rognmo O. Comparison of Three Popular Exercise Modalities on V O2max in Overweight and Obese. Med Sci Sports Exerc. 2016 Mar;48(3):491-8. doi: 10.1249/MSS.0000000000000777.

Reference Type RESULT
PMID: 26440134 (View on PubMed)

Other Identifiers

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TRENO

Identifier Type: -

Identifier Source: org_study_id

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