Interval Training in Young Healthy Individuals

NCT ID: NCT00733941

Last Updated: 2015-05-27

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 24 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2008-09-30
• Study Completion Date: 2009-12-31

Brief Summary

Individuals who participate in regular physical exercise possess a lower prevalence of cardiovascular risk factors such as hypertension, type 2 diabetes, obesity and hypercholesterolemia, and aerobic exercise is therefore considered an important adjuvant therapy in risk factor modification and to promote health.

The main focus of the present study is therefore to detect how rapid it is possible to increase aerobic capacity with interval running exercise.

The hypothesis is that it is possible to improve maximal oxygen uptake faster when increasing training frequency. The total gain in maximal oxygen uptake will however be the same between the two groups when they have performed the same amount of training

Detailed Description

We will perform aerobic interval training at an intensity of 90-95% of maximum heart rate in healthy individuals. The subjects will be randomly assigned to carry out a total of 24 exercise-sessions, either at 3 times per week or 8 times per week.

The two groups will carry out 24 training sessions before 8 weeks of detraining will provide how rapidly aerobic capacity is lost due to inactivity. After the detraining period a retraining phase is introduced to detect if improvements in aerobic capacity occur more rapidly compared to before the first training period

The subjects will be tested for oxygen uptake, pumping capacity of the heart, blood volume, skeletal muscle enzyme activity, endothelial function.

Conditions

Healthy Subjects; Exercise Test

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: TREATMENT
• Blinding Strategy: NONE

Study Groups

High frequency training

24 interval exercises performed 8 times per week

Group Type: EXPERIMENTAL

High frequency training

Intervention Type: BEHAVIORAL

24 training sessions, 8x weekly, followed by detraining phase 8 weeks, and retraining

Normal frequency training

24 interval exercises performed 3 times per week

Group Type: EXPERIMENTAL

normal frequence training

Intervention Type: BEHAVIORAL

24 training sessions, 3x weekly, followed by detraining phase 8 weeks, and retraining

Interventions

High frequency training

24 training sessions, 8x weekly, followed by detraining phase 8 weeks, and retraining

Intervention Type: BEHAVIORAL

normal frequence training

24 training sessions, 3x weekly, followed by detraining phase 8 weeks, and retraining

Intervention Type: BEHAVIORAL

Eligibility Criteria

Inclusion Criteria

• BMI<27, non-smokers, train less that 1-2 times per week, VO2max <60 for male and <50 for female.

Exclusion Criteria

• Hypertension, diabetes and cardiovascular disease.

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 27 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

Norwegian University of Science and Technology

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

Øivind Rognmo, PhD

Role: PRINCIPAL_INVESTIGATOR

Norwegian University of Science and Technology

Ulrik Wisløff, Professor

Role: PRINCIPAL_INVESTIGATOR

National Taiwan Normal University

Locations

Norwegian University of Science and Technology

Trondheim, , Norway

NTNU

Trondheim, , Norway

Countries

Norway

References

Hatle H, Stobakk PK, Molmen HE, Bronstad E, Tjonna AE, Steinshamn S, Skogvoll E, Wisloff U, Ingul CB, Rognmo O. Effect of 24 sessions of high-intensity aerobic interval training carried out at either high or moderate frequency, a randomized trial. PLoS One. 2014 Feb 7;9(2):e88375. doi: 10.1371/journal.pone.0088375. eCollection 2014.

Reference Type: RESULT

PMID: 24516645 (View on PubMed)

Other Identifiers

4.2008.1755

Identifier Type: -

Identifier Source: org_study_id