Mechanisms of Exercise-Induced Hypoalgesia

NCT ID: NCT06050889

Last Updated: 2024-04-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-11-14

Study Completion Date

2024-04-19

Brief Summary

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Exercise-Induced Hypoalgesia (EIH) is a lessening of pain sensitivity in response to an acute bout of exercise. Limited research has examined the effects of expectations on EIH during a dynamic resistance training during different intensities. Therefore, the purpose of this study is to examine the effects of positive and negative expectations on EIH.

Detailed Description

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Individuals who meet the eligibility criteria and consent to participate will attend one testing session that is approximately one hour. Baseline Pressure Pain Threshold will be measured followed by random assignment to one of four study arms.

Conditions

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Healthy

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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High Intensity Exercise

Participants will complete an upper body resistance exercise until they report a high fatigue level.

Group Type EXPERIMENTAL

Positive Expectations Instructional Set

Intervention Type OTHER

Participants randomly assigned to this instructional set will be told, "You will be completing an intervention known to be effective for some people with shoulder pain. We expect this will make you less sensitive to the pressure applied to your shoulder and thigh and you will require more pressure than what was previously necessary to experience pain."

Negative Expectations Instructional Set

Intervention Type OTHER

Participants randomly assigned to this instructional set will be told, "You will be completing an intervention which is not effective for some people with shoulder pain. We expect this will make you more sensitive to the pressure applied to your shoulder and thigh and you will require less pressure than what was previously necessary to experience pain."

Low Intensity Exercise

Participants will complete an upper body resistance exercise until they report a low fatigue level.

Group Type EXPERIMENTAL

Positive Expectations Instructional Set

Intervention Type OTHER

Participants randomly assigned to this instructional set will be told, "You will be completing an intervention known to be effective for some people with shoulder pain. We expect this will make you less sensitive to the pressure applied to your shoulder and thigh and you will require more pressure than what was previously necessary to experience pain."

Negative Expectations Instructional Set

Intervention Type OTHER

Participants randomly assigned to this instructional set will be told, "You will be completing an intervention which is not effective for some people with shoulder pain. We expect this will make you more sensitive to the pressure applied to your shoulder and thigh and you will require less pressure than what was previously necessary to experience pain."

Interventions

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Positive Expectations Instructional Set

Participants randomly assigned to this instructional set will be told, "You will be completing an intervention known to be effective for some people with shoulder pain. We expect this will make you less sensitive to the pressure applied to your shoulder and thigh and you will require more pressure than what was previously necessary to experience pain."

Intervention Type OTHER

Negative Expectations Instructional Set

Participants randomly assigned to this instructional set will be told, "You will be completing an intervention which is not effective for some people with shoulder pain. We expect this will make you more sensitive to the pressure applied to your shoulder and thigh and you will require less pressure than what was previously necessary to experience pain."

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Pain Free

Exclusion Criteria

* Non-English speaking
* Regular use of prescription pain medications
* Current or history of chronic pain condition
* Currently taking blood-thinning medication
* Any blood clotting disorder, such as hemophilia
* Systemic medical condition known to affect sensation, such as uncontrolled diabetes or neurological conditions
* Not physically ready to exercise without a medical exam as indicated by the Physical Activity Readiness Questionnaire Plus (PAR-Q+)
* Not have had Surgery, injury, or fracture within the past 6 months
Minimum Eligible Age

18 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of Central Florida

OTHER

Sponsor Role lead

Responsible Party

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Abigail Wilson

Assistant Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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University of Central Florida

Orlando, Florida, United States

Site Status

Countries

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United States

Other Identifiers

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6

Identifier Type: -

Identifier Source: org_study_id

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