The Effect of Soluble Fiber Dextrin on Subjective and Physiological Markers of Appetite

NCT ID: NCT04596969

Last Updated: 2020-10-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

50 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-01-01

Study Completion Date

2018-01-01

Brief Summary

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This study examines the effect of soluble fiber dextrin on food intake, appetite, and physiological markers of appetite. Adults aged 18-45 years with a BMI were recruited for this study. Participants were given two doses of SFD in the morning and appetite, food intake and physiological markers of appetite were measured over 10 years.

Detailed Description

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Overweight and obesity are leading health problems. The study investigates the effect of a food ingredient from two different sources at two different doses on food intake and appetite markers over a 10 hour period. All participants reported to the laboratory first thing in the morning and remained in the laboratory until after their evening meal. A fixed breakfast was served but the participants were free to eat as much as they liked at lunch and dinner. Blood was taken at regular intervals during the day and assayed for glucose and several hormones related to appetite. Subjective measures of appetite were also collected over the 10 hour test session.

Conditions

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Appetitive Behavior

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Human subjects
Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

DOUBLE

Participants Investigators
Material was provided in coded plain packaging. Participants and researchers were unaware of what was being received.

Study Groups

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SFD Tapioca 20g

20g soluble fiber dextrin derived from tapioca

Group Type EXPERIMENTAL

Soluble Fiber Dextrin

Intervention Type OTHER

Ingredient based on resistant starch

SFD Tapioca 40g

40g soluble fiber dextrin derived from tapioca

Group Type EXPERIMENTAL

Soluble Fiber Dextrin

Intervention Type OTHER

Ingredient based on resistant starch

SFD corn 20g

40g soluble fiber dextrin derived from corn

Group Type EXPERIMENTAL

Soluble Fiber Dextrin

Intervention Type OTHER

Ingredient based on resistant starch

SFD corn 40g

Group Type EXPERIMENTAL

Soluble Fiber Dextrin

Intervention Type OTHER

Ingredient based on resistant starch

Control

Maltodextrin

Group Type PLACEBO_COMPARATOR

Soluble Fiber Dextrin

Intervention Type OTHER

Ingredient based on resistant starch

Interventions

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Soluble Fiber Dextrin

Ingredient based on resistant starch

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

BMI 19.9 - 29.9 Aged 18-45 Find the study foods to be palatable

Exclusion Criteria

Weight change \> 3kg in the past three months Do not regularly consume snacks Presence or history of GI disorders Restrained eater Used medication that influences appetite
Minimum Eligible Age

18 Years

Maximum Eligible Age

45 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Iowa State University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Other Identifiers

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SFDISU

Identifier Type: -

Identifier Source: org_study_id

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