Satiety Response of Four Dietary Fibers

NCT ID: NCT01233024

Last Updated: 2012-03-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

EARLY_PHASE1

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-11-30

Study Completion Date

2012-02-29

Brief Summary

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Studies have found a relationship between dietary fiber consumption and body weight regulation. This relationship may stem from enhanced satiety through fermentation of certain fibers in the large intestine.

The objective of this study is to determine and compare satiety ratings, changes in food intake, and gastrointestinal effects for four fibers: fructooligosaccharide, inulin, soluble corn fiber, and resistant starch.

Detailed Description

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Conditions

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Healthy

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

PREVENTION

Blinding Strategy

TRIPLE

Participants Investigators Outcome Assessors

Study Groups

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Low fiber control

no treatment dinner bar, no treatment breakfast bar

Group Type PLACEBO_COMPARATOR

Control

Intervention Type DIETARY_SUPPLEMENT

Dinner bar fortified with 0g fiber; breakfast bar fortified with 0g dietary fiber.

Promitor soluble corn fiber

12g in dinner bar, 11g in breakfast bar

Group Type EXPERIMENTAL

Soluble corn fiber

Intervention Type DIETARY_SUPPLEMENT

Dinner bar fortified with 12g fiber; breakfast bar fortified with 11g dietary fiber.

FiberSym resistant starch

12g in dinner bar, 11g breakfast bar

Group Type EXPERIMENTAL

Resistant starch

Intervention Type DIETARY_SUPPLEMENT

Dinner bar fortified with 12g fiber; breakfast bar fortified with 11g dietary fiber.

Orafti P95 fructooligosaccharide

12g in dinner bar, 11g in breakfast bar

Group Type EXPERIMENTAL

Fructooligosaccharide

Intervention Type DIETARY_SUPPLEMENT

Dinner bar fortified with 12g fiber; breakfast bar fortified with 11g dietary fiber.

Orafti HPX inulin

12g in dinner bar, 11g in breakfast bar

Group Type EXPERIMENTAL

Inulin

Intervention Type DIETARY_SUPPLEMENT

Dinner bar fortified with 12g fiber; breakfast bar fortified with 11g dietary fiber.

Interventions

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Control

Dinner bar fortified with 0g fiber; breakfast bar fortified with 0g dietary fiber.

Intervention Type DIETARY_SUPPLEMENT

Soluble corn fiber

Dinner bar fortified with 12g fiber; breakfast bar fortified with 11g dietary fiber.

Intervention Type DIETARY_SUPPLEMENT

Resistant starch

Dinner bar fortified with 12g fiber; breakfast bar fortified with 11g dietary fiber.

Intervention Type DIETARY_SUPPLEMENT

Fructooligosaccharide

Dinner bar fortified with 12g fiber; breakfast bar fortified with 11g dietary fiber.

Intervention Type DIETARY_SUPPLEMENT

Inulin

Dinner bar fortified with 12g fiber; breakfast bar fortified with 11g dietary fiber.

Intervention Type DIETARY_SUPPLEMENT

Other Intervention Names

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Low fiber control Promitor soluble corn fiber FiberSym resistant starch Orafti P95 fructooligosaccharide Orafti HPX inulin

Eligibility Criteria

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Inclusion Criteria

* Healthy women
* Age 18-40 years
* Nonsmoking
* Not taking weight loss medications
* Non-dieting (weight has not changed more than 11 pounds over three months)
* BMI between 18.5 and 29
* Spoken and written English literacy

Exclusion Criteria

* Do not regularly consume breakfast
* Food allergies to wheat, soy, peanut, or dairy
* BMI less than 25 or greater than 29 upon admission to study
* Cancer diagnosis in past 5 years
* History of heart disease, kidney disease, diabetes, or eating disorder
* History of ulcerative colitis, Crohn's disease, or any other gastrointestinal condition
* History of drug or alcohol abuse in past 6 months
* Use of lipid-lowering, anti-hypertensive, or anti-inflammatory steroid medication
* Concurrent or recent (within 30 days) intervention study participation
* Pregnant or lactating
* Irregular menstrual cycle
* Vegetarians
* People who eat more than approximately 15 grams of fiber per day
Minimum Eligible Age

18 Years

Maximum Eligible Age

40 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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University of Minnesota

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Joanne L Slavin, PhD

Role: PRINCIPAL_INVESTIGATOR

University of Minnesota

Locations

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University of Minnesota

Saint Paul, Minnesota, United States

Site Status

Countries

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United States

Other Identifiers

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1003E78714

Identifier Type: -

Identifier Source: org_study_id

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