Resistant Starch Type-3, Glucose Metabolism and Appetite

NCT ID: NCT05108142

Last Updated: 2021-11-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

8 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-11-01

Study Completion Date

2020-03-15

Brief Summary

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Resistant starch (RS) is considered to have many of the same health benefits as dietary fiber. The aim of this study was to examine the effects of RS3 on postprandial glycemic and insulinemic responses and appetite.

Healthy males (aged 18-35 years) participated in this study. Subjects were provided meals in the laboratory after overnight fasting on two separate occasions, at least 1 week apart. On each laboratory visit, subjects were given either a control meal (COM) or an RS3 meal (RSM). Both meals during the two visits consisted of vegetarian pasta and were matched for energy intake, composition, ingredients, and amount, but were prepared in different ways. The COM was hot, freshly cooked pasta, while the RSM was re-heated pasta that had been cooked the previous day and chilled overnight. Blood samples and subjective appetite ratings were collected at fasting and for a period of 3 h after meal consumption (i.e., 15-min intervals for glucose and 30-min intervals for insulin, ghrelin, and subjective appetite).

Detailed Description

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Conditions

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Resistant Starch

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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Control meal

Participants were asked to visit the lab and consume the control meal (hot, freshly cooked pasta)

Group Type EXPERIMENTAL

Dietary intervention

Intervention Type OTHER

fresh, hot pasta and re-heated pasta

Resistant starch meal

Participants were asked to visit the lab and consume the resistant starch meal (re-heated pasta)

Group Type EXPERIMENTAL

Dietary intervention

Intervention Type OTHER

fresh, hot pasta and re-heated pasta

Interventions

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Dietary intervention

fresh, hot pasta and re-heated pasta

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Healthy males
* Aged between 18 and 40 years
* Normal weight (BMI 18.5-24.9 kg/m2)
* No history of serious disease or currently taking any medications
* Not dieting or seeking to lose weight.

Exclusion Criteria

* Smokers
* Allergy to gluten-containing products, lactose intolerance, or dairy allergy
* Particular dislike to any of the foods provided during the study.
Minimum Eligible Age

18 Years

Maximum Eligible Age

40 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

Yes

Sponsors

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King Saud University

OTHER

Sponsor Role lead

Responsible Party

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Maha Alhussain

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Maha Alhussain

Riyadh, , Saudi Arabia

Site Status

Countries

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Saudi Arabia

Other Identifiers

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19/01008

Identifier Type: -

Identifier Source: org_study_id