Gas Exchange Kinetics and Work Load During Exercise

NCT ID: NCT03770507

Last Updated: 2021-02-12

Basic Information

• Recruitment Status: WITHDRAWN
• Clinical Phase: NA
• Study Classification: INTERVENTIONAL
• Study Start Date: 2016-04-25
• Study Completion Date: 2016-04-25

Brief Summary

The purpose of this research study is to understand how different kinds of exercise affect the human body and the health of the heart and lungs. For example, some people like to exercise continuously for relatively long periods of time while others like to exercise for short periods of time with rest periods in between. Children tend to exercise in frequent bouts of brief exercise interspersed with periods of rest. Also, some people like running or treadmill exercise while others like to work out on stationary bicycles. To date, standard exercise testing is based on a century-old paradigm used predominantly for adults that involves maximal exercise protocols (cardiopulmonary exercise testing-CPET). Moreover, different but widely used exercise modalities such as cycle ergometer and treadmills are currently impossible to compare in children, and this has limited the clinical and research application of such testing in the pediatric age-range. A major premise of this laboratory is that laboratory testing of cardiopulmonary fitness in children should be based on protocols that mimic naturally occurring patterns of exercise in children, rather than those that have been artificially employed to assess maximal efforts in adults. This research project designed to begin the process of systematically identifying protocols can be best used for children and young adults. Participants will exercise in different protocols on a bicycle ergometer or treadmill. This research could lead to improved and more accurate fitness assessment and pave the way to an improved personalized exercise program in health and illness.

Conditions

Methods of Exercise in Children

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: CROSSOVER
• Primary Study Purpose: BASIC_SCIENCE
• Blinding Strategy: SINGLE

Study Groups

Treadmill Exercise in Adolescents and Adults

Comparison of gas exchange kinetics between treadmill and cyclo ergometer exercises

Group Type: EXPERIMENTAL

Exercise Training

Intervention Type: OTHER

Comparison of stationary bike and treadmill exercise among adolescents and adults

Cyclo Ergometer Exercise in Adolescents and Adults

Comparison of gas exchange kinetics between treadmill and cyclo ergometer exercises

Group Type: EXPERIMENTAL

Exercise Training

Intervention Type: OTHER

Comparison of stationary bike and treadmill exercise among adolescents and adults

Interventions

Exercise Training

Comparison of stationary bike and treadmill exercise among adolescents and adults

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• Between the ages of 7-35 years old without any known respiratory, cardiac or metabolic disease
• Determined to be in good health by preparticipation history
• No evidence of disease or disability that would impair participation in an exercise testing
• No chronic prescribed medication

Exclusion Criteria

• Other limitation which in the eyes of the physician that would preclude ability to perform exercise testing
• Use of illegal drugs or abuse of alcohol
• Pregnancy or breastfeeding

• Minimum Eligible Age: 7 Years
• Maximum Eligible Age: 35 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

University of California, Irvine

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Locations

Pediatric Exercise and Genomics Research Center, University of California, Irvine

Irvine, California, United States

Countries

United States

Provided Documents

Document Type: Study Protocol

View Document

Other Identifiers

2015-2467

Identifier Type: -

Identifier Source: org_study_id