Effects of Aerobic Training Program On Liver Functions

NCT ID: NCT05704608

Last Updated: 2023-01-30

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 30 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2021-09-01
• Study Completion Date: 2022-11-30

Brief Summary

The liver plays a central role in energy exchange, protein synthesis as well as the elimination of waste products from the body. The optimal functioning of the liver is essential for athletic performance. It becomes necessary to maintain the enzymes of the liver at an optimal level so that liver cells can be protected from inflammation or damage. This paper investigated the effects of a twelve-week aerobic exercise program on the liver function of adult athletes. A total of thirty (30) healthy male athletes aged 21 to 24 were recruited for this study and kept in two equal groups. The control group was kept under rigorous supervision and did not participate in any special activities. The experiment group was well-versed in their assigned training program and solely performed the experimental procedure for twelve (12) weeks. Evaluation of all patients in both experimental and control groups was carried out before and after the treatment program by measuring the levels of (Alkaline phosphate, AST/SGOT, ALT/SGPT, Bilirubin Total/indirect/direct, Albumin, Globulin, and Total protein) respectively using standard methods by collecting blood samples, 5 mls each of baseline into lithium heparin containers for estimation of above biochemical parameters at the pathology laboratory accredited by National Accreditation Board for Testing and Calibration Laboratories accredited (NABL, India).

Conditions

Liver Functions

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: OTHER
• Blinding Strategy: DOUBLE

Study Groups

Experimental Group

Aerobic training program was performed by participants.

Group Type: EXPERIMENTAL

Aerobic training

Intervention Type: OTHER

Exercises on a treadmill at different speeds and inclination were performed.

Control group

No intervention was performed by the participants.

Group Type: NO_INTERVENTION

No interventions assigned to this group

Interventions

Aerobic training

Exercises on a treadmill at different speeds and inclination were performed.

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• Male
• Age: 21-24 years
• Healthy
• Athletes

Exclusion Criteria

• history of severe illness,
• surgery, or damage to liver,
• fatty liver disease,
• cirrhosis,
• blood infections,
• neuromuscular illnesses,
• or the presence of any disorders such as fever, high blood pressure, high blood sugar

• Minimum Eligible Age: 21 Years
• Maximum Eligible Age: 24 Years
• Eligible Sex: MALE
• Accepts Healthy Volunteers: Yes

Sponsors

King Saud University

OTHER

Sponsor Role: lead

Responsible Party

Masood Khan

Principal Investigator

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Masood Khan, M.P.Th

Role: PRINCIPAL_INVESTIGATOR

King Saud University

Locations

King Saud University

Riyadh, , Saudi Arabia

Countries

Saudi Arabia

Other Identifiers

DN 4900 /FSS

Identifier Type: -

Identifier Source: org_study_id