Propofol and Sevoflurane for Catheter-Related Bladder Discomfort

NCT ID: NCT02252445

Last Updated: 2016-09-01

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

82 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-11-30

Study Completion Date

2015-01-31

Brief Summary

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The investigators want to evaluate the efficacy of the propofol and sevoflurane for the prevention of catheter-related bladder discomfort.

Detailed Description

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The mechanism of catheter-related bladder discomfort is thought to be related to the muscarinic receptor. Propofol and desflurane are most widely used as an anesthetic agent. Propofol and desflurane are known to block the muscarinic receptor in different ways.

The investigators want to evaluate the efficacy of the propofol and sevoflurane for the prevention of catheter-related bladder discomfort.

Conditions

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Catheter Site Discomfort Complications Anesthesia Urinary Bladder Neoplasms

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

TRIPLE

Participants Investigators Outcome Assessors

Study Groups

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Propofol

Propofol will be administered as the anesthetic maintenance agent.

Group Type ACTIVE_COMPARATOR

Propofol

Intervention Type DRUG

Propofol will be administered.

Sevoflurane

Sevoflurane will be administered as the anesthetic maintenance agent.

Group Type EXPERIMENTAL

Sevoflurane

Intervention Type DRUG

Sevoflurane will be administered.

Interventions

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Propofol

Propofol will be administered.

Intervention Type DRUG

Sevoflurane

Sevoflurane will be administered.

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Patients scheduled for transurethral bladder excision under general anesthesia
* ASA I-III

Exclusion Criteria

* Foley catheter less than 18 Fr.
* Patients with obstruction of urinary tract
* Patients with neurogenic bladder
* Patients with severe obesity
* Patients with neurologic disorder
* Patients with chronic pain
* Patients with allergic history to propofol or sevoflurane
Minimum Eligible Age

19 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Seoul National University Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Seolu National University of Hospital

Seoul, , South Korea

Site Status

Countries

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South Korea

Other Identifiers

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CRBDPPFSEVO

Identifier Type: -

Identifier Source: org_study_id

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