Sevoflurane Versus Desflurane for Catheter-related Bladder Discomfort

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

108 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-05-31

Study Completion Date

2014-07-31

Brief Summary

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We want to evaluate the efficacy of the sevoflurane and desflurane for the prevention of catheter-related bladder discomfort.

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Detailed Description

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The mechanism of catheter-related bladder discomfort is thought to be related to the muscarinic receptor. The volatile anesthetics such as sevoflurane and desflurane are known to block the muscarinic receptor in different ways.

We want to evaluate the efficacy of the sevoflurane and desflurane for the prevention of catheter-related bladder discomfort.

Conditions

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Catheter Site Discomfort Complications Anesthesia Urinary Bladder Neoplasms

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

TRIPLE

Participants Investigators Outcome Assessors

Study Groups

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Sevoflurane

Sevoflurane will be administered as the maintenance agent of general anesthesia.

Group Type EXPERIMENTAL

Sevoflurane

Intervention Type DRUG

Sevoflurane will be used.

Desflurane

Desflurane will be administered as the maintenance agent of general anesthesia.

Group Type ACTIVE_COMPARATOR

Desflurane

Intervention Type DRUG

Desflurane will be used

Interventions

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Sevoflurane

Sevoflurane will be used.

Intervention Type DRUG

Desflurane

Desflurane will be used

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Patients scheduled for transurethral bladder excision under general anesthesia
* ASA I-III

Exclusion Criteria

* Bladder outflow obstruction
* Overactive bladder
* End-stage renal disease
* Neurogenic bladder
* Heart failure
* Arrhythmia
* Morbid obesity
* Use of chronic analgesic medication
* Hepatic disease
* Pulmonary disease
* Psychiatric disease

Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No