Influence of Sevoflurane and Desflurane on Postoperative Sore Throat

NCT ID: NCT03259672

Last Updated: 2017-08-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

100 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-10-01

Study Completion Date

2018-11-01

Brief Summary

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This investigation is planned to compare the incidence and severity of postoperative sore throat according to the use of sevoflurane or desflurane.

Detailed Description

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Conditions

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Hip Arthroplasty

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

TRIPLE

Participants Investigators Outcome Assessors

Study Groups

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Sevoflurane

Group Type ACTIVE_COMPARATOR

Sevoflurane

Intervention Type DRUG

Sevoflurane was used as a maintenance anesthetic agent.

Desflurane

Group Type EXPERIMENTAL

Desflurane

Intervention Type DRUG

Desflurane was used as a maintenance anesthetic agent.

Interventions

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Sevoflurane

Sevoflurane was used as a maintenance anesthetic agent.

Intervention Type DRUG

Desflurane

Desflurane was used as a maintenance anesthetic agent.

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* ASA I-III
* Patients scheduled for general anesthesia with endotracheal intubation

Exclusion Criteria

* Difficult airway
* Friable teeth
* Rapid sequence induction
* Recent sore throat
* Recent upper respiratory infection
* Asthma
* Chronic obstructive pulmonary disease
* Chronic cough
* Arrhythmia
* Coronary disease
* Heart failure
* Pregnancy
* Allergy to sevoflurane
* Allergy to desflurane
* Fever after halogenated anesthetics
* Jaundice after halogenated anesthetics
* Malignant hyperthremia
* Allergy to remifentanil
* Friable teeth
* History of head and neck surgery
* Multiple intubation attempts
* Regional anesthetic agents
* Gastric tube
* Dexamethasone
* Severe hypovolemia
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Keimyung University Dongsan Medical Center

OTHER

Sponsor Role lead

Responsible Party

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Hyun-Chang Kim

Assistant professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Other Identifiers

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SevoDesPOST

Identifier Type: -

Identifier Source: org_study_id

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