Desflurane and Sevoflurane Minimal Flow Anesthesia on Recovery and Anesthetic Depth
NCT ID: NCT05024084
Last Updated: 2021-09-20
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
PHASE4
130 participants
INTERVENTIONAL
2021-09-05
2021-10-01
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
SUPPORTIVE_CARE
DOUBLE
Study Groups
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Group Sevoflurane
The patients in this arm will be given Sevoflurane (2-3%) as volatile anesthetic throughout the duration of anesthesia.
Minimal flow anesthesia (fresh gas flow <0.5 l/min) using Sevoflurane
Sevoflurane will be used for the maintenance of general anesthesia which will be carried out using a fresh gas flow of less than 0,5 l/min
Group Desflurane
The patients in this arm will be given Desflurane (7-8%) as volatile anesthetic throughout the duration of anesthesia.
Minimal flow anesthesia (fresh gas flow <0.5 l/min) using Desflurane
Desflurane will be used for the maintenance of general anesthesia which will be carried out using a fresh gas flow of less than 0,5 l/min
Interventions
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Minimal flow anesthesia (fresh gas flow <0.5 l/min) using Sevoflurane
Sevoflurane will be used for the maintenance of general anesthesia which will be carried out using a fresh gas flow of less than 0,5 l/min
Minimal flow anesthesia (fresh gas flow <0.5 l/min) using Desflurane
Desflurane will be used for the maintenance of general anesthesia which will be carried out using a fresh gas flow of less than 0,5 l/min
Eligibility Criteria
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Inclusion Criteria
* Patients undergoing elective surgery under general anesthesia
* Patients with an American Society of Anesthesiologists Classification I or II
Exclusion Criteria
* Emergency surgery
* Patients with a contraindication for minimal flow anesthesia
* Uncontrolled diabetes mellitus
* History of serious systemic disease (cardiac, pulmonary, hepatic)
* Utilization of another analgesic technique such as central or peripheral nerve blocks
18 Years
65 Years
ALL
No
Sponsors
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Ufuk University
OTHER
Responsible Party
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Baturay Kansu Kazbek
Principal Investigator
Principal Investigators
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Baturay K Kazbek, Ass. Prof.
Role: PRINCIPAL_INVESTIGATOR
Ufuk University Faculty of Medicine Department of Anesthesiology and Reanimation
Locations
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Ufuk University Dr. Rıdvan Ege Hospital
Ankara, , Turkey (Türkiye)
Countries
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Central Contacts
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Facility Contacts
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References
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Taskin D, Gedik E, Kayhan Z. Effects of Minimal Flow Sevoflurane or Desflurane Anaesthesia on Hemodynamic Parameters, Body Temperature and Anaesthetic Consumption. Turk J Anaesthesiol Reanim. 2020 Oct;48(5):356-363. doi: 10.5152/TJAR.2020.39699. Epub 2020 May 5.
Werner JG, Castellon-Larios K, Thongrong C, Knudsen BE, Lowery DS, Antor MA, Bergese SD. Desflurane Allows for a Faster Emergence When Compared to Sevoflurane without Affecting the Baseline Cognitive Recovery Time. Front Med (Lausanne). 2015 Oct 28;2:75. doi: 10.3389/fmed.2015.00075. eCollection 2015.
Other Identifiers
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2021-009
Identifier Type: -
Identifier Source: org_study_id
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