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Desflurane and Sevoflurane on Remifentanil Requirement

NCT ID: NCT06123624

Last Updated: 2023-11-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Clinical Phase

NA

Total Enrollment

78 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-11-27

Study Completion Date

2024-08-30

Brief Summary

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The primary purpose of this study is to compare the desflurane and sevoflurane on remifentanil requirement using analgesia nociception index-guided anesthesia in patients undergoing spine surgery.

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Detailed Description

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Conditions

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Spinal Diseases

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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Desflurane group

Group Type EXPERIMENTAL

Desflurane Inhalation Solution

Intervention Type DRUG

Keeping the anesthesia using desflurane inhalation solution as 1 minimal alveolar concentration

Sevoflurane group

Group Type PLACEBO_COMPARATOR

Sevoflurane Inhalation Solution

Intervention Type DRUG

Keeping the anesthesia using sevoflurane inhalation solution as 1 minimal alveolar concentration

Interventions

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Desflurane Inhalation Solution

Keeping the anesthesia using desflurane inhalation solution as 1 minimal alveolar concentration

Intervention Type DRUG

Sevoflurane Inhalation Solution

Keeping the anesthesia using sevoflurane inhalation solution as 1 minimal alveolar concentration

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Clinical diagnosis of herniated disc, injury of spinal cord, and neoplasm of spinal meninges

Exclusion Criteria

* Hyperbilirubinemia
* Prior chronic pain
* Prior opioid abuse
* Cardiac arrythmia
Minimum Eligible Age

19 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Ajou University School of Medicine

OTHER

Sponsor Role lead

Responsible Party

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Ji Eun Kim

Assistant professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Other Identifiers

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AJOUIRB-IV-2023-380

Identifier Type: -

Identifier Source: org_study_id

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