Comparison of Volatile Anesthetics on Cerebral Oxygenation During Controlled Hypotension

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

95 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-06-30

Study Completion Date

2016-08-31

Brief Summary

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Controlled hypotension is a preferred method for reducing surgical bleeding during septoplasty operations however, the level of hypotension and bradycardia should not disrupt cerebral oxygenation. On this account, the investigators aim to investigate the effects of different volatile anesthetics combined with a short-acting opioid on cerebral oxygenation during controlled hypotension using near infrared spectroscopy.

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Detailed Description

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Conditions

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Oxygen Saturation

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

DOUBLE

Participants Outcome Assessors

Study Groups

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Sevoflurane

Group Type EXPERIMENTAL

Sevoflurane

Intervention Type DRUG

Sevoflurane %2-3 for general anesthesia maintenance

Desflurane

Group Type EXPERIMENTAL

Desflurane

Intervention Type DRUG

Desflurane %6-8 for general anesthesia maintenance

Interventions

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Sevoflurane

Sevoflurane %2-3 for general anesthesia maintenance

Intervention Type DRUG

Desflurane

Desflurane %6-8 for general anesthesia maintenance

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Patients in American Society of Anesthesiology (ASA) classification I and II
* Patients undergoing elective septoplasty operation

Exclusion Criteria

* Patients in ASA classification III and higher
* Emergency surgery
* Patients in New York Heart Association classification III-IV
* Patients with known allergy to drugs used in the study

Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No