Sevoflurane/Dexmedetomidine vs. Isoflurane for Pediatric Emergence Delirium
NCT ID: NCT06624592
Last Updated: 2025-12-16
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
RECRUITING
PHASE3
400 participants
INTERVENTIONAL
2024-12-20
2026-11-01
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
RANDOMIZED
PARALLEL
TREATMENT
SINGLE
Study Groups
Review each arm or cohort in the study, along with the interventions and objectives associated with them.
Isoflurane group
Isoflurane
Subjects will receive standard of care anesthesia Isoflurane
Sevoflurane group
Sevoflurane
Subjects will receive standard of care anesthesia Sevoflurane, with intravenous push Dexmedetomidine
Interventions
Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.
Sevoflurane
Subjects will receive standard of care anesthesia Sevoflurane, with intravenous push Dexmedetomidine
Isoflurane
Subjects will receive standard of care anesthesia Isoflurane
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
* Surgeries include ENT cases (i.e., tonsillectomy/adenoidectomy), ophthalmology cases (i.e., strabismus), and urology cases.
* Can be outpatient or General Care inpatient procedures.
* All cases must include an IV and an endotracheal tube (ETT).
Exclusion Criteria
* TIVA cases.
* No PIV in place during the case, planned PICU admission postoperatively.
* Previous history of severe emergence delirium documented by a provider (via interventions or explicitly stated).
2 Years
7 Years
ALL
No
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
Mayo Clinic
OTHER
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Lindsay L. Warner
Principal Investigator
Principal Investigators
Learn about the lead researchers overseeing the trial and their institutional affiliations.
Lindsay Warner, MD
Role: PRINCIPAL_INVESTIGATOR
Mayo Clinic
Locations
Explore where the study is taking place and check the recruitment status at each participating site.
Mayo Clinic in Rochester
Rochester, Minnesota, United States
Countries
Review the countries where the study has at least one active or historical site.
Central Contacts
Reach out to these primary contacts for questions about participation or study logistics.
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
24-002252
Identifier Type: -
Identifier Source: org_study_id