The Quality of Recovery After General Anesthesia With Desflurane and Sevoflurane in Endoscopic Ureteral Lithotripsy
NCT ID: NCT04712162
Last Updated: 2021-01-15
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
60 participants
INTERVENTIONAL
2019-11-19
2020-05-07
Brief Summary
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Detailed Description
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Statistical analysis was performed by using Kaplan-Meieir curve and log-rank test for time to adequate depth of anesthesia and time to awakening; t-test for time to wash-out of volatile anesthetics; chi-square test for depth of anesthesia by PRST score, irritation after awakening and Aldrete score; Fisher test for adverse effects of volatile anesthetics.
The research was approved by Gia Dinh People Hospital ethics committee
Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
NONE
Study Groups
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D: maintain anesthesia with desflurane
D: maintain anesthesia with Suprane® (Desflurane) at 6%. Volatile concentration was titrated according to end-tidal MAC to maintain 0.7-1.3 MAC using end-tidal monitor of Dräger Primus anesthesia machine.
Other
Compare time to awakening and quality of recovery after general anesthesia between two groups.
S: maintain anesthesia with sevoflurane.
S: maintain anesthesia with Sevorane® (Sevoflurane) at 2%. Volatile concentration was titrated according to end-tidal MAC to maintain 0.7-1.3 MAC using end-tidal monitor of Dräger Primus anesthesia machine.
Other
Compare time to awakening and quality of recovery after general anesthesia between two groups.
Interventions
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Other
Compare time to awakening and quality of recovery after general anesthesia between two groups.
Eligibility Criteria
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Inclusion Criteria
* ASA I and II
Exclusion Criteria
* Indication for conversion to tracheal intubation during surgery.
* History of malignant hyperthermia.
* Pregnancy.
* Obese (BMI \>25 kg/m2).
* Substances abuse.
18 Years
70 Years
ALL
No
Sponsors
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Gia Dinh People Hospital
OTHER
Responsible Party
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Principal Investigators
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Thanh T. Nguyen, PhD
Role: STUDY_CHAIR
Gia Dinh People Hospital
Locations
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Anesthesiology Department of Gia Dinh People Hospital
Ho Chi Minh City, , Vietnam
Countries
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References
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Bruhn J, Bouillon TW, Shafer SL. Bispectral index (BIS) and burst suppression: revealing a part of the BIS algorithm. J Clin Monit Comput. 2000;16(8):593-6. doi: 10.1023/A:1012216600170.
Drover DR, Lemmens HJ, Pierce ET, Plourde G, Loyd G, Ornstein E, Prichep LS, Chabot RJ, Gugino L. Patient State Index: titration of delivery and recovery from propofol, alfentanil, and nitrous oxide anesthesia. Anesthesiology. 2002 Jul;97(1):82-9. doi: 10.1097/00000542-200207000-00012.
Eger EI 2nd, Saidman LJ, Brandstater B. Minimum alveolar anesthetic concentration: a standard of anesthetic potency. Anesthesiology. 1965 Nov-Dec;26(6):756-63. doi: 10.1097/00000542-196511000-00010. No abstract available.
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Rampil IJ, Lockhart SH, Zwass MS, Peterson N, Yasuda N, Eger EI 2nd, Weiskopf RB, Damask MC. Clinical characteristics of desflurane in surgical patients: minimum alveolar concentration. Anesthesiology. 1991 Mar;74(3):429-33. doi: 10.1097/00000542-199103000-00007.
Whitlock EL, Villafranca AJ, Lin N, Palanca BJ, Jacobsohn E, Finkel KJ, Zhang L, Burnside BA, Kaiser HA, Evers AS, Avidan MS. Relationship between bispectral index values and volatile anesthetic concentrations during the maintenance phase of anesthesia in the B-Unaware trial. Anesthesiology. 2011 Dec;115(6):1209-18. doi: 10.1097/ALN.0b013e3182395dcb.
Aldrete JA. Post-anesthetic recovery score. J Am Coll Surg. 2007 Nov;205(5):e3-4; author reply e4-5. doi: 10.1016/j.jamcollsurg.2007.07.034. No abstract available.
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Choi GJ, Baek CW, Kang H, Park YH, Yang SY, Shin HY, Jung YH, Woo YC, Lee UL. Emergence agitation after orthognathic surgery: a randomised controlled comparison between sevoflurane and desflurane. Acta Anaesthesiol Scand. 2015 Feb;59(2):224-31. doi: 10.1111/aas.12435. Epub 2014 Nov 14.
De Oliveira GS Jr, Fitzgerald PC, Ahmad S, Marcus RJ, McCarthy RJ. Desflurane/fentanyl compared with sevoflurane/fentanyl on awakening and quality of recovery in outpatient surgery using a laryngeal mask airway: a randomized, double-blinded controlled trial. J Clin Anesth. 2013 Dec;25(8):651-8. doi: 10.1016/j.jclinane.2013.07.006. Epub 2013 Oct 4.
Dogru K, Yildiz K, Madenoglu H, Boyaci A. Early recovery properties of sevoflurane and desflurane in patients undergoing total hip replacement surgery. Curr Ther Res Clin Exp. 2003 May;64(5):301-9. doi: 10.1016/S0011-393X(03)00086-9.
Green MS, Green P, Neubert L, Voralu K, Saththasivam P, Mychaskiw G. Recovery following desflurane versus sevoflurane anesthesia for outpatient urologic surgery in elderly females. Anesth Pain Med. 2015 Feb 1;5(1):e22271. doi: 10.5812/aapm.22271. eCollection 2015 Feb.
Kaur A, Jain AK, Sehgal R, Sood J. Hemodynamics and early recovery characteristics of desflurane versus sevoflurane in bariatric surgery. J Anaesthesiol Clin Pharmacol. 2013 Jan;29(1):36-40. doi: 10.4103/0970-9185.105792.
La Colla L, Albertin A, La Colla G, Mangano A. Faster wash-out and recovery for desflurane vs sevoflurane in morbidly obese patients when no premedication is used. Br J Anaesth. 2007 Sep;99(3):353-8. doi: 10.1093/bja/aem197. Epub 2007 Jul 9.
Mahmoud NA, Rose DJ, Laurence AS. Desflurane or sevoflurane for gynaecological day-case anaesthesia with spontaneous respiration? Anaesthesia. 2001 Feb;56(2):171-4. doi: 10.1046/j.1365-2044.2001.01528.x.
Mikuni I, Harada S, Yakushiji R, Iwasaki H. Effects of changing from sevoflurane to desflurane on the recovery profile after sevoflurane induction: a randomized controlled study. Can J Anaesth. 2016 Mar;63(3):290-7. doi: 10.1007/s12630-015-0514-9. Epub 2015 Oct 20.
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Smajic J, Praso M, Hodzic M, Hodzic S, Srabovic-Okanovic A, Smajic N, Djonlagic Z. Assessment of depth of anesthesia: PRST score versus bispectral index. Med Arh. 2011;65(4):216-20. doi: 10.5455/medarh.2011.65.216-220.
Werner JG, Castellon-Larios K, Thongrong C, Knudsen BE, Lowery DS, Antor MA, Bergese SD. Desflurane Allows for a Faster Emergence When Compared to Sevoflurane without Affecting the Baseline Cognitive Recovery Time. Front Med (Lausanne). 2015 Oct 28;2:75. doi: 10.3389/fmed.2015.00075. eCollection 2015.
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Other Identifiers
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81/CN-HĐĐĐ
Identifier Type: -
Identifier Source: org_study_id
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