Comparison Between Propofol-remifentanil Total Intravenous Anesthesia and Desflurane-remifentanil Balanced Anesthesia With Regard to Post-anesthetic Functional Recovery Measured With QoR-40 in Vitrectomy

NCT ID: NCT02212340

Last Updated: 2016-09-27

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

84 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-07-31

Study Completion Date

2016-03-31

Brief Summary

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Total intravenous anesthesia (TIVA) and inhalation anesthesia are both widely and safely used, and there are many clinical trials comparing these on various aspects of anesthesia. However, there have not been studies comparing the quality of recovery from the different methods of general anesthesia in vitrectomy. In this study, the investigators compare the functional recovery after general anesthesia in TIVA and inhalation anesthesia with QoR-40 questionnaire in vitrectomy.

Detailed Description

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Conditions

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Vitrectomy Operation Under General Anesthesia

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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TIVA group

Anesthesia is maintained with fresofol and remifentanil

Group Type EXPERIMENTAL

fresofol and remifentanil

Intervention Type DRUG

Anesthesia is maintained with fresofol and remifentanil in TIVA group or with desflurane and remifentanil in Des group according to randomly allocated group.

Des group

Anesthesia is maintained with desflurane and remifentanil

Group Type ACTIVE_COMPARATOR

desflurane and remifentanil

Intervention Type DRUG

Anesthesia is maintained with fresofol and remifentanil in TIVA group or with desflurane and remifentanil in Des group according to randomly allocated group.

Interventions

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fresofol and remifentanil

Anesthesia is maintained with fresofol and remifentanil in TIVA group or with desflurane and remifentanil in Des group according to randomly allocated group.

Intervention Type DRUG

desflurane and remifentanil

Anesthesia is maintained with fresofol and remifentanil in TIVA group or with desflurane and remifentanil in Des group according to randomly allocated group.

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

1. Patients (20-80 years old) scheduled for vitrectomy surgery undergoing general anesthesia.
2. ASA 1-3

Exclusion Criteria

1. Patients with allergy to anesthetic agents
2. Anticipated difficult airway
3. BMI \> 30 kg/m2
4. Chronic obstructive pulmonary disease
5. Heart failure 6. Unstable angina
Minimum Eligible Age

20 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Yonsei University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Gangnam Severance Hospital, Yonsei University College of Medicine

Seoul, Seoul, South Korea

Site Status

Countries

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South Korea

Other Identifiers

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3-2014-0104

Identifier Type: -

Identifier Source: org_study_id

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