Comparison of PRS According to Inhalation Agent During LDLT

NCT ID: NCT01886664

Last Updated: 2014-06-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

70 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-12-31

Study Completion Date

2013-12-31

Brief Summary

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The investigators tried to evaluate the effect of desflurane on the incidence of postreperfusion syndrome during living donor liver transplantation surgery. The investigators used sevoflurane as a comparison.

Detailed Description

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Conditions

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Liver Transplantation Postreperfusion Syndrome

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

SINGLE

Participants

Study Groups

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Sevoflurane

Performing liver transplantation under general anesthesia using sevoflurane

Group Type ACTIVE_COMPARATOR

sevoflurane

Intervention Type DRUG

Desflurane

Performing liver transplantation under general anesthesia using desflurane

Group Type EXPERIMENTAL

Desflurane

Intervention Type DRUG

Interventions

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sevoflurane

Intervention Type DRUG

Desflurane

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* elective LDLT

Exclusion Criteria

* age \< 18, age \> 65
* patient refusal
* re-transplantation
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Seoul National University Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Seoul National University Hospital

Seoul, Seoul, South Korea

Site Status

Countries

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South Korea

References

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Lee J, Yoo YJ, Lee JM, Park YJ, Ryu HG. Sevoflurane Versus Desflurane on the Incidence of Postreperfusion Syndrome During Living Donor Liver Transplantation: A Randomized Controlled Trial. Transplantation. 2016 Mar;100(3):600-6. doi: 10.1097/TP.0000000000000874.

Reference Type DERIVED
PMID: 26335917 (View on PubMed)

Other Identifiers

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Des vs Sevo PRS

Identifier Type: -

Identifier Source: org_study_id

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