A Comparison of Propofol Based Total Intravenous Anesthesia and Sevoflurane Based Balanced Anesthesia on Renal Protection During Lung Transplantation Under Extracorporeal Membrane Oxygenation - A Prospective, Randomized Trial

NCT ID: NCT02009280

Last Updated: 2016-08-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2013-11-30

Study Completion Date

2016-07-31

Brief Summary

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The aim of this study is to investigate whether propofol based total intravenous anesthesia reduces incidence of acute kidney injury following the lung transplantation under extracorporeal membrane oxygenation

Detailed Description

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Conditions

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Patients Undergoing Lung Transplantation Under Extracorporeal Membrane Oxygenation

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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Propofol group

Propofol group

Group Type EXPERIMENTAL

Administration of anesthesia: Propofol

Intervention Type DRUG

Maintenance of anesthesia with the propofol

Sevoflurane group

Sevoflurane group

Group Type ACTIVE_COMPARATOR

Administration of anesthesia: Sevoflurane

Intervention Type DRUG

Maintenance of anesthesia with the sevoflurane

Interventions

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Administration of anesthesia: Propofol

Maintenance of anesthesia with the propofol

Intervention Type DRUG

Administration of anesthesia: Sevoflurane

Maintenance of anesthesia with the sevoflurane

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Sixty adults undergoing lung transplantation under extracorporeal membrane oxygenation

Exclusion Criteria

* Patient having propofol allergy, BMI \> 30 kg/m2
Minimum Eligible Age

20 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Yonsei University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Department of Anesthesiology and Pain Medicine, Severance Hospital, Yonsei University Health System

Seoul, , South Korea

Site Status

Countries

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South Korea

Other Identifiers

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4-2013-0648

Identifier Type: -

Identifier Source: org_study_id

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