Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
UNKNOWN
NA
118 participants
INTERVENTIONAL
2010-09-30
2015-06-30
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
Related Clinical Trials
Explore similar clinical trials based on study characteristics and research focus.
Cerebral Substrates of Prospective Memory in Young and Its Disruption in Normal Aging and in Alzheimer's Disease: A Study in Anatomical MRI, Diffusion Tensor MRI and Functional MRI
NCT02522091
Multi-modal Neuroimaging in Alzheimer's Disease
NCT01638949
Optimization of MRI Sequences Used in the Study of Neurodegenerative Diseases
NCT05929144
Memory Imaging of Normal Aging
NCT00315575
Multi-modal Neuroimaging in Alzheimer's Disease
NCT01554202
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
NON_RANDOMIZED
FACTORIAL
DIAGNOSTIC
NONE
Study Groups
Review each arm or cohort in the study, along with the interventions and objectives associated with them.
Young Healthy Subjects
Memory assessment
Neuropsychological tests including clinical and original tests to compare differences between each populations
Structural MRI
to compare differences between each populations
Functional MRI
to compare differences between each populations
Virtual reality / Memory assessment
to compare differences between each populations
Middle age Healthy Subjects
Memory assessment
Neuropsychological tests including clinical and original tests to compare differences between each populations
Structural MRI
to compare differences between each populations
Functional MRI
to compare differences between each populations
Virtual reality / Memory assessment
to compare differences between each populations
Elderly Healthy Subjects
Memory assessment
Neuropsychological tests including clinical and original tests to compare differences between each populations
Structural MRI
to compare differences between each populations
Functional MRI
to compare differences between each populations
Virtual reality / Memory assessment
to compare differences between each populations
Mild Cognitive Impairment patients
Memory assessment
Neuropsychological tests including clinical and original tests to compare differences between each populations
Structural MRI
to compare differences between each populations
Functional MRI
to compare differences between each populations
Virtual reality / Memory assessment
to compare differences between each populations
Alzheimer Disease patients
Memory assessment
Neuropsychological tests including clinical and original tests to compare differences between each populations
Structural MRI
to compare differences between each populations
Functional MRI
to compare differences between each populations
Virtual reality / Memory assessment
to compare differences between each populations
Interventions
Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.
Memory assessment
Neuropsychological tests including clinical and original tests to compare differences between each populations
Structural MRI
to compare differences between each populations
Functional MRI
to compare differences between each populations
Virtual reality / Memory assessment
to compare differences between each populations
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
* Native language: French
* Beck \< 7
* Medical, neurological, neuropsychological and neuroradiological depth in accordance with the criteria for inclusion and exclusion-specific population, that is to say:
* Young Healthy Subjects: between 18 and 44 years old;
* Middle age Healthy Subjects: between 45 and 69 years old; without memory complaints, normal performances compared to the age and the educational level for all tests of the diagnostic battery.
* Elderly Healthy Subjects: over 70 years old, without memory complaints, normal performances compared to the age and the educational level for all tests of the diagnostic battery.
* MCI patients: over 50 years old, presenting the current criteria for amnestic MCI including: i) memory complaint, ii) deficits of the episodic memory (lower performance of at least 1 SD from the norm for age and cultural level for one or more scores of episodic memory and iii) normal performances compared to the age and the educational level of all other cognitive functions as memory, including tests to assess cognitive abilities.
* Alzheimer's patients: over 50 years old, presenting the standard criteria of NINCDS-ADRDA probable Alzheimer's disease, including abnormal global cognitive function and deficits in at least two cognitive domains identified by the diagnostic battery and a mild to moderate Alzheimer's disease (MMSE ≥ 18).
Exclusion Criteria
* A chronic neurological, psychiatric, endocrine, hepatic or infectious complaint
* A history of major disease (a lung, heart, metabolic, hematologic, endocrine disease or a severe cancer);
* A medication that may interfere with memory or metabolic measures
* A alcohol or drugs abuse
* claustrophobia, metallic object in the body
* A predominantly left-hand (score below 50% in Edinburgh Inventory).
* Protected adults, and persons not affiliated with a social security system will not participate in this study.
* Pregnant or suckling women
* The inclusion of a participant in another biomedical research protocol (during the study or within 12 months before inclusion)
18 Years
ALL
Yes
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
Institut National de la Santé Et de la Recherche Médicale, France
OTHER_GOV
University Hospital, Caen
OTHER
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Principal Investigators
Learn about the lead researchers overseeing the trial and their institutional affiliations.
Vincent de La Sayette, MD
Role: PRINCIPAL_INVESTIGATOR
University Hospital, Caen
Locations
Explore where the study is taking place and check the recruitment status at each participating site.
GIP Cyceron
Caen, Calvados, France
MRSH - University of Caen
Caen, Calvados, France
University Hospital Côte de Nacre
Caen, , France
Countries
Review the countries where the study has at least one active or historical site.
Central Contacts
Reach out to these primary contacts for questions about participation or study logistics.
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
2010-A00031-38
Identifier Type: -
Identifier Source: org_study_id
More Related Trials
Additional clinical trials that may be relevant based on similarity analysis.