Technical Development of Multi-Parametric Renocerebral MRI

NCT ID: NCT02831335

Last Updated: 2025-10-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

120 participants

Study Classification

OBSERVATIONAL

Study Start Date

2026-12-01

Study Completion Date

2032-12-31

Brief Summary

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The purpose of the study is to investigate the associations of the age-related changes in the brain, kidneys and cognitive performance in healthy adults by utilizing multiple anatomic and functional MRI methods along with a battery of cognitive tests.

Detailed Description

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Conditions

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Aging

Study Design

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Observational Model Type

COHORT

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Group 1

normal 21-35 years old participants

MRI

Intervention Type OTHER

Perform MRI studies

Group 2

normal 36-50 years old participants

MRI

Intervention Type OTHER

Perform MRI studies

Group 3

normal 51-65 years old participants

MRI

Intervention Type OTHER

Perform MRI studies

Group 4

normal 66- 80 years old participants

Group 4

Intervention Type OTHER

Perform MRI studies

Interventions

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MRI

Perform MRI studies

Intervention Type OTHER

MRI

Perform MRI studies

Intervention Type OTHER

MRI

Perform MRI studies

Intervention Type OTHER

Group 4

Perform MRI studies

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

1. English-speaking as primary language
2. No hearing loss or uncorrected vision

Exclusion Criteria

1. Lacking capacity to consent
2. Having known history of cardiovascular diseases (e.g., clinical stroke)
3. Having acute and chronic obstructive pulmonary disease
4. Having known history of renal diseases (e.g., acute kidney injury)
5. Having known history of cognitive disorder or psychiatric illness
6. Having known history of chemical dependence (e.g., alcohol and narcotics)
7. Being treated with stimulant medications, anticonvulsants, antihypertensives or ß-adrenergic blockers
Minimum Eligible Age

21 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of Minnesota

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Xiufeng Li, Ph.D.

Role: PRINCIPAL_INVESTIGATOR

University of Minnesota

Locations

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Center for Magnetic Resonance Research

Minneapolis, Minnesota, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Xiufeng Li, Ph.D.

Role: CONTACT

6126258258

Facility Contacts

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Xiufeng Li, PhD

Role: primary

612-625-8258

Other Identifiers

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1603M85492

Identifier Type: -

Identifier Source: org_study_id

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