Study of Motor Representations in Healthy Subjects and Amnestic MCI
NCT ID: NCT02574182
Last Updated: 2021-07-12
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
COMPLETED
97 participants
OBSERVATIONAL
2015-02-24
2017-05-13
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
Related Clinical Trials
Explore similar clinical trials based on study characteristics and research focus.
Prospective Memory Imaging
NCT01638884
Cerebral Substrates of Prospective Memory in Young and Its Disruption in Normal Aging and in Alzheimer's Disease: A Study in Anatomical MRI, Diffusion Tensor MRI and Functional MRI
NCT02522091
Functional Neuroimaging in Parkinson's Disease
NCT04904068
Magnetic Resonance Imaging Studies of Motor and Thought Processes
NCT00001361
Imaging Study of Automatic Movements
NCT00031382
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
CASE_CONTROL
PROSPECTIVE
Study Groups
Review each arm or cohort in the study, along with the interventions and objectives associated with them.
Control subjects under 40 years
Brain MRI Simulated walking with Corvit boots Records gait parameters on Gaitrite carpet
Brain MRI
Brain MRI (Magnetic Resonance Imaging) brain is a painless test that allows to visualize the different brain structures.
Korvit, device made up of 2 shoes which reproduces the feeling to go. The Korvit® system appears possible to analyze the activated cerebral zones and to thus try to better understand the operation of the brain during walk.
The GAITRite is a carpet for recording the walking operating parameters
Control subjects over 60 years
Brain MRI Simulated walking with Corvit boots Records gait parameters on Gaitrite carpet
Brain MRI
Brain MRI (Magnetic Resonance Imaging) brain is a painless test that allows to visualize the different brain structures.
Korvit, device made up of 2 shoes which reproduces the feeling to go. The Korvit® system appears possible to analyze the activated cerebral zones and to thus try to better understand the operation of the brain during walk.
The GAITRite is a carpet for recording the walking operating parameters
MCI subjects over 60 years
Brain MRI Simulated walking with Corvit boots Records gait parameters on Gaitrite carpet
Brain MRI
Brain MRI (Magnetic Resonance Imaging) brain is a painless test that allows to visualize the different brain structures.
Korvit, device made up of 2 shoes which reproduces the feeling to go. The Korvit® system appears possible to analyze the activated cerebral zones and to thus try to better understand the operation of the brain during walk.
The GAITRite is a carpet for recording the walking operating parameters
Interventions
Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.
Brain MRI
Brain MRI (Magnetic Resonance Imaging) brain is a painless test that allows to visualize the different brain structures.
Korvit, device made up of 2 shoes which reproduces the feeling to go. The Korvit® system appears possible to analyze the activated cerebral zones and to thus try to better understand the operation of the brain during walk.
The GAITRite is a carpet for recording the walking operating parameters
Other Intervention Names
Discover alternative or legacy names that may be used to describe the listed interventions across different sources.
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
* Age above 18 years
* Lack dementia as NICDS-ADRDA criteria
* Lack of pre-existing musculoskeletal disorders, regardless of the cause (except MCI).
* Absence of a history of stroke or other cerebrovascular disease with spinal sensorimotor sequelae.
* No cons-indication for performing a brain MRI.
* Witennses, population of young (\<40 years)
* Witnesses ,population of older subjects (\> 60 years)
* Witnesses Lack of MCI
* MCI patients, criteria MCI criteria according to Dubois
Exclusion Criteria
* Contraindications to brain MRI.
18 Years
ALL
Yes
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
University Hospital, Angers
OTHER_GOV
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Principal Investigators
Learn about the lead researchers overseeing the trial and their institutional affiliations.
Michael Dinomais, MD
Role: PRINCIPAL_INVESTIGATOR
UH Angers
Locations
Explore where the study is taking place and check the recruitment status at each participating site.
University Hospital Angers
Angers, Pays de la Loire Region, France
Countries
Review the countries where the study has at least one active or historical site.
References
Explore related publications, articles, or registry entries linked to this study.
Dinomais M, Minassian AT, Tuilier T, Delion M, Wilke M, N'Guyen S, Richard I, Aube C, Menei P. Functional MRI comparison of passive and active movement: possible inhibitory role of supplementary motor area. Neuroreport. 2009 Oct 7;20(15):1351-5. doi: 10.1097/WNR.0b013e328330cd43.
Beauchet O, Allali G, Berrut G, Hommet C, Dubost V, Assal F. Gait analysis in demented subjects: Interests and perspectives. Neuropsychiatr Dis Treat. 2008 Feb;4(1):155-60. doi: 10.2147/ndt.s2070.
Rimmer E, Wojciechowska M, Stave C, Sganga A, O'Connell B. Implications of the Facing Dementia Survey for the general population, patients and caregivers across Europe. Int J Clin Pract Suppl. 2005 Mar;(146):17-24. doi: 10.1111/j.1368-504x.2005.00482.x.
Ogawa S, Lee TM, Nayak AS, Glynn P. Oxygenation-sensitive contrast in magnetic resonance image of rodent brain at high magnetic fields. Magn Reson Med. 1990 Apr;14(1):68-78. doi: 10.1002/mrm.1910140108.
Beauchet O, Allali G, Launay C, Herrmann FR, Annweiler C. Gait variability at fast-pace walking speed: a biomarker of mild cognitive impairment? J Nutr Health Aging. 2013 Mar;17(3):235-9. doi: 10.1007/s12603-012-0394-4.
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
CHU PROMOTEUR 2014/32
Identifier Type: -
Identifier Source: org_study_id
More Related Trials
Additional clinical trials that may be relevant based on similarity analysis.