VIsual Cerebral ConnecTivity On Functional Magnetic Resonance Imaging in Patients With Hereditary REtinal Dystrophies

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

200 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-01-04

Study Completion Date

2028-07-31

Brief Summary

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The Rothschild Foundation A Hospital follows a cohort of approximately 300 patients with hereditary retinal dystrophy. These patients are followed in ophthalmology consultation every year. In order to plan the MRI on the day of the annual consultation and to avoid additional travel for patients, patients will be informed of the study before the consultation (transmission of an information letter and the information note from study). If patients agree to participate in the study, rMRI will be scheduled. During the follow-up ophthalmologic consultation, after checking the inclusion and non-inclusion criteria, the study information will be repeated, and patients who still agree to participate will sign the study consent.

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Detailed Description

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Conditions

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Vision Functional Brain Networks in Patients With Hereditary Retinal Dystrophies

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Patients for whom there is no planned implant surgery

IRMf-r (séquence resting state)

Intervention Type DEVICE

Functional MRI of functional brain networks

Patients for whom implantation surgery is planned

IRMf-r (séquence resting state)

Intervention Type DEVICE

Functional MRI of functional brain networks

case

IRMf-r (séquence resting state)

Intervention Type DEVICE

Functional MRI of functional brain networks

Interventions

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IRMf-r (séquence resting state)

Functional MRI of functional brain networks

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Patient over 18 years old
* Diagnostic clinique de dystrophie rétinienne héréditaire ou maculopathie héréditaire, syndromique ou non syndromique
* Artificial vision treatment such as a retinal implant, or optogenetics scheduled in the next 6 months
* Express consent to participate in the study
* Affiliate or beneficiary of a social security scheme

Exclusion Criteria

* Patient benefiting from a legal protection measure
* Pregnant or breastfeeding woman
* Contraindication to MRI (claustrophobia, implanted equipment such as pacemaker).
* Other additional ocular pathology that can significantly affect vision
* Recent eye surgery less than 3 months old

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No