Cerebellar Loops and Attention Deficit Hyperactivity Disorder (ADHD)

NCT ID: NCT00684931

Last Updated: 2009-06-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

NA

Total Enrollment

19 participants

Study Classification

INTERVENTIONAL

Study Start Date

2008-02-29

Study Completion Date

2008-07-31

Brief Summary

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The aim of this study is to investigate the integrity of connectivity between the neocortex and the cerebellum in the Attention Deficit Hyperactivity Disorder (ADHD). Fibers integrity will be measured using magnetic Resonance Imaging Techniques.

Detailed Description

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ADHD is a neurodevelopmental trouble characterized by attentional deficits, impulsivity and motor hyperactivity. Morphological neuroimaging studies in ADHD children have revealed cerebellar abnormalities, however data in adults regarding cerebellum alterations are scarce. In this study we will analyse the conectivity of the cerebellum of adults ADHD patients. We will use diffusion tensor imaging (DTI) technique, and morphological data will be compared with the neuropsychological status.

Conditions

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Attention Deficit Disorder With Hyperactivity

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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1

patients with Attention Deficit Disorder with or without Hyperactivity

Group Type EXPERIMENTAL

Imaging

Intervention Type OTHER

neuropsychological evaluation and Imaging with magnetic resonance (MRI)

2

healthy volunteer without Attention Deficit Hyperactivity Disorder

Group Type SHAM_COMPARATOR

Imaging

Intervention Type OTHER

neuropsychological evaluation and Imaging with magnetic resonance (MRI)

Interventions

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Imaging

neuropsychological evaluation and Imaging with magnetic resonance (MRI)

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

Patient with ADHD :

* Diagnosis of ADHD
* 18 - 35 years old

Healthy volunteer :

* 18 - 35 years old
* no ADHD diagnosed

Exclusion Criteria

* Associated neurological or psychiatric pathologies
* Pregnant woman
* MRI counter indication
Minimum Eligible Age

18 Years

Maximum Eligible Age

35 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University Hospital, Bordeaux

OTHER

Sponsor Role lead

Responsible Party

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University Hospital, Bordeaux

Principal Investigators

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Manuel BOUVARD, MD

Role: PRINCIPAL_INVESTIGATOR

Charles Perrens Hospital

Locations

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Charles Perrens Hospital

Bordeaux, , France

Site Status

University Hospital Bordeaux

Bordeaux, , France

Site Status

Countries

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France

Other Identifiers

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CHUBX 2007/21

Identifier Type: -

Identifier Source: org_study_id

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