Study of Iron Accumulation Measured in MRI in Non-pathological Aging

NCT ID: NCT04659824

Last Updated: 2025-05-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

190 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-01-30

Study Completion Date

2029-01-31

Brief Summary

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To study the correlation between the iron load in brain, measured in MRI, and the age of healthy subjects Secondary objectives are to study the correlations between the iron load in cortical brain regions and (i) the cognitive performances, (ii) markers of aging (MRI, EEG, OCT, biology),and (iii) demographical factors involved in iron load.

Detailed Description

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Conditions

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Healthy Aging

Study Design

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Observational Model Type

COHORT

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Healthy

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Men or women between 18 and 95 years old
* French speaker with capability to understand the instructions
* Health insurance

Exclusion Criteria

* Pregnancy
* minor subject
* no informed consent agreement
* subject enrolled in pharmaceutic study or exclusion period
* MRI contra-indications
* Neurological or psychiatric disorders
* MOCA \< 26
* Psychotropic drugs
* More than 3 MRI exams
* More than 1 neuropsychological assessment (same cognitive tests) in the last 12 months
* Unable to follow the entire protocol according to the investigator
Minimum Eligible Age

18 Years

Maximum Eligible Age

95 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University Hospital, Lille

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Grégory KUCHCINSKI, MD

Role: PRINCIPAL_INVESTIGATOR

University Hospital, Lille

Locations

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Hopital Roger Salengro, CHU Lille

Lille, , France

Site Status RECRUITING

Countries

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France

Central Contacts

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Grégory KUCHCINSKI, MD

Role: CONTACT

0320445962 ext. +33

Other Identifiers

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2020-A00491-38

Identifier Type: OTHER

Identifier Source: secondary_id

2019_24

Identifier Type: -

Identifier Source: org_study_id

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