Resistance Exercise in Healthy Men

NCT ID: NCT01220037

Last Updated: 2013-10-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

34 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-04-30

Study Completion Date

2011-12-31

Brief Summary

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In the present study, the effects of age and dietary intake will be assessed on myocellular characteristics during 72 hours after a resistance type exercise session.

Detailed Description

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Conditions

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Single Bout of Resistance Type Exercise Standardized Diet

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

DOUBLE

Investigators Outcome Assessors

Study Groups

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Young regular diet

During the time of the study this group will adhere to a standardized regular diet.

Group Type EXPERIMENTAL

Adhere to a specific standardized diet for 4 days

Intervention Type BEHAVIORAL

24 h before the start of the intervention all subjects will adhere to a standardized diet for 4 days. Young subjects are randomly allocated to either a low protein diet, regular protein diet or high protein diet group. All elderly subjects will adhere to a regular protein diet comparable to the regular protein diet of the young subjects.

Young low protein diet

During the time of the study this group will adhere to a standardized low protein diet.

Group Type EXPERIMENTAL

Adhere to a specific standardized diet for 4 days

Intervention Type BEHAVIORAL

24 h before the start of the intervention all subjects will adhere to a standardized diet for 4 days. Young subjects are randomly allocated to either a low protein diet, regular protein diet or high protein diet group. All elderly subjects will adhere to a regular protein diet comparable to the regular protein diet of the young subjects.

Young high protein

During the time of the study this group will adhere to a standardized high protein diet.

Group Type EXPERIMENTAL

Adhere to a specific standardized diet for 4 days

Intervention Type BEHAVIORAL

24 h before the start of the intervention all subjects will adhere to a standardized diet for 4 days. Young subjects are randomly allocated to either a low protein diet, regular protein diet or high protein diet group. All elderly subjects will adhere to a regular protein diet comparable to the regular protein diet of the young subjects.

Elderly

During the time of the study this group will adhere to a standardized high protein diet

Group Type EXPERIMENTAL

Adhere to a specific standardized diet for 4 days

Intervention Type BEHAVIORAL

24 h before the start of the intervention all subjects will adhere to a standardized diet for 4 days. Young subjects are randomly allocated to either a low protein diet, regular protein diet or high protein diet group. All elderly subjects will adhere to a regular protein diet comparable to the regular protein diet of the young subjects.

Interventions

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Adhere to a specific standardized diet for 4 days

24 h before the start of the intervention all subjects will adhere to a standardized diet for 4 days. Young subjects are randomly allocated to either a low protein diet, regular protein diet or high protein diet group. All elderly subjects will adhere to a regular protein diet comparable to the regular protein diet of the young subjects.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* healthy men between the ages of 18-30 or 70-85 years

Exclusion Criteria

* Subjects with a recent history or current state of cardiovascular disease, COPD, Parkinson, rheumatoid arthritis, musculoskeletal/orthopaedic disorders, renal disorder, cognitive impairment.
Minimum Eligible Age

18 Years

Maximum Eligible Age

85 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

Yes

Sponsors

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Maastricht University Medical Center

OTHER

Sponsor Role lead

Responsible Party

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Lex Verdijk

Dr.

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Maastricht University Medical Centre

Maastricht, Zuid Limburg, Netherlands

Site Status

Countries

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Netherlands

References

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Snijders T, Verdijk LB, McKay BR, Smeets JS, van Kranenburg J, Groen BB, Parise G, Greenhaff P, van Loon LJ. Acute dietary protein intake restriction is associated with changes in myostatin expression after a single bout of resistance exercise in healthy young men. J Nutr. 2014 Feb;144(2):137-45. doi: 10.3945/jn.113.183996. Epub 2013 Dec 4.

Reference Type DERIVED
PMID: 24306214 (View on PubMed)

Other Identifiers

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MEC 09-3-080

Identifier Type: -

Identifier Source: org_study_id