Protein Intake Distribution to Support Muscle Anabolism in Healthy Young Adults
NCT ID: NCT07245199
Last Updated: 2025-11-24
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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NOT_YET_RECRUITING
NA
36 participants
INTERVENTIONAL
2026-01-31
2027-01-01
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
OTHER
NONE
Study Groups
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BALANCED
protein intake
4x 25 g
SIP
Protein intake
15x 7 g
BOLUS
protein intake
1x 100g
Interventions
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protein intake
1x 100g
protein intake
4x 25 g
Protein intake
15x 7 g
Eligibility Criteria
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Inclusion Criteria
* Healthy
* 18.5 ≤ BMI 30 ≤ kg・m-2
Exclusion Criteria
* Sports/exercise \>4 sessions/week or a structured resistance or endurance training schedule
* Lactose intolerant or allergies to milk protein
* A history of neuromuscular problems
* Use of anticoagulation medication
* Individuals on any medications known to affect protein metabolism (i.e. , non-steroidal anti-inflammatories, or prescription acne medications).
* Strict vegetarian
* Injury or condition that would limit the participant from performing the resistance exercise.
* Pregnancy
* Hormone replacement therapy
* Blood donation within the past 2 months
18 Years
40 Years
ALL
Yes
Sponsors
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Maastricht University Medical Center
OTHER
Responsible Party
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Locations
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Maastricht University
Maastricht, , Netherlands
Countries
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References
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Mamerow MM, Mettler JA, English KL, Casperson SL, Arentson-Lantz E, Sheffield-Moore M, Layman DK, Paddon-Jones D. Dietary protein distribution positively influences 24-h muscle protein synthesis in healthy adults. J Nutr. 2014 Jun;144(6):876-80. doi: 10.3945/jn.113.185280. Epub 2014 Jan 29.
Areta JL, Burke LM, Ross ML, Camera DM, West DW, Broad EM, Jeacocke NA, Moore DR, Stellingwerff T, Phillips SM, Hawley JA, Coffey VG. Timing and distribution of protein ingestion during prolonged recovery from resistance exercise alters myofibrillar protein synthesis. J Physiol. 2013 May 1;591(9):2319-31. doi: 10.1113/jphysiol.2012.244897. Epub 2013 Mar 4.
Other Identifiers
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NL-010056 / METC25-038
Identifier Type: OTHER
Identifier Source: secondary_id
NL-010056 / METC25-038
Identifier Type: -
Identifier Source: org_study_id
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