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Leucine Supplementation in Elderly Men

NCT ID: NCT00807508

Last Updated: 2008-12-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE1/PHASE2

Total Enrollment

29 participants

Study Classification

INTERVENTIONAL

Study Start Date

2007-01-31

Study Completion Date

2008-12-31

Brief Summary

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In the present study the investigators aim to determine whether leucine supplementation can augment muscle mass and strength and improve body composition in healthy elderly men

Detailed Description

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Conditions

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Sarcopenia Atrophy Aging

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Study Groups

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1

daily leucine supplementation

Group Type EXPERIMENTAL

leucine

Intervention Type DIETARY_SUPPLEMENT

daily leucine capsules with each main meal

2

daily placebo supplementation

Group Type PLACEBO_COMPARATOR

placebo

Intervention Type DIETARY_SUPPLEMENT

wheat meal capsules with each main meal

Interventions

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placebo

wheat meal capsules with each main meal

Intervention Type DIETARY_SUPPLEMENT

leucine

daily leucine capsules with each main meal

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* living independently

Exclusion Criteria

* Diabetes cardiovascular disease orthopedic limitations history of resistance training in past 5 years
Minimum Eligible Age

65 Years

Maximum Eligible Age

85 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

Yes

Sponsors

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Maastricht University Medical Center

OTHER

Sponsor Role lead

Responsible Party

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MaastrichtUMC

Principal Investigators

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Luc JC van Loon, PhD

Role: PRINCIPAL_INVESTIGATOR

Maastricht University Medical Center

Locations

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Maastricht University Medical Centre

Maastricht, , Netherlands

Site Status

Countries

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Netherlands

References

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Verhoeven S, Vanschoonbeek K, Verdijk LB, Koopman R, Wodzig WK, Dendale P, van Loon LJ. Long-term leucine supplementation does not increase muscle mass or strength in healthy elderly men. Am J Clin Nutr. 2009 May;89(5):1468-75. doi: 10.3945/ajcn.2008.26668. Epub 2009 Mar 25.

Reference Type DERIVED
PMID: 19321567 (View on PubMed)

Other Identifiers

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MEC 06-3-062A

Identifier Type: -

Identifier Source: org_study_id