Protein Supplementation to Promote Muscle Protein Anabolism in Frail Elderly People
NCT ID: NCT01109628
Last Updated: 2025-04-04
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
65 participants
INTERVENTIONAL
2009-11-30
2011-07-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
QUADRUPLE
Study Groups
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Protein drink
Protein drink
Twice a day during 6 months
Placebo drink
Placebo drink
Twice a day during 6 months
Interventions
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Protein drink
Twice a day during 6 months
Placebo drink
Twice a day during 6 months
Eligibility Criteria
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Inclusion Criteria
* Able to understand and perform the study procedures
Exclusion Criteria
* No recent history (within 2 years) of participating in any regular resistance exercise training program (general questionnaire)
* Use of anti-coagulation medication (except of Acetyl Salicyl acid)
* Renal insufficiency (eGFR \<60 mL/min/1.73 m2)
* Allergic or sensitive for milk proteins
65 Years
ALL
No
Sponsors
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Maastricht University Medical Center
OTHER
Top Institute Food and Nutrition
OTHER
Wageningen University
OTHER
Responsible Party
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Lisette de Groot
Professor
Locations
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Wageningen University
Wageningen, Gelderland, Netherlands
Countries
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References
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van de Rest O, van der Zwaluw NL, Tieland M, Adam JJ, Hiddink GJ, van Loon LJ, de Groot LC. Effect of resistance-type exercise training with or without protein supplementation on cognitive functioning in frail and pre-frail elderly: secondary analysis of a randomized, double-blind, placebo-controlled trial. Mech Ageing Dev. 2014 Mar-Apr;136-137:85-93. doi: 10.1016/j.mad.2013.12.005. Epub 2013 Dec 27.
van der Zwaluw NL, van de Rest O, Tieland M, Adam JJ, Hiddink GJ, van Loon LJ, de Groot LC. The impact of protein supplementation on cognitive performance in frail elderly. Eur J Nutr. 2014 Apr;53(3):803-12. doi: 10.1007/s00394-013-0584-9. Epub 2013 Sep 18.
Tieland M, van de Rest O, Dirks ML, van der Zwaluw N, Mensink M, van Loon LJ, de Groot LC. Protein supplementation improves physical performance in frail elderly people: a randomized, double-blind, placebo-controlled trial. J Am Med Dir Assoc. 2012 Oct;13(8):720-6. doi: 10.1016/j.jamda.2012.07.005. Epub 2012 Aug 11.
Other Identifiers
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A1002-1
Identifier Type: -
Identifier Source: org_study_id
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