The Effect of Leucine on Carnitine Transport to Skeletal Muscle

NCT ID: NCT05009654

Last Updated: 2021-08-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

16 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-10-01

Study Completion Date

2018-01-31

Brief Summary

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The primary aim of the current research project is to explore whether leucine stimulates carnitine transport, and thus affecting muscle carnitine content.

A secondary aim of this project is to investigate the effect of carnitine with leucine supplementation on muscle strength and body composition.

Detailed Description

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Conditions

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Muscle Loss

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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carnitine + leucine

1000 mg L-carnitine with 3000 mg L-leucine per day for 24 weeks

Group Type EXPERIMENTAL

L-carnitine

Intervention Type DIETARY_SUPPLEMENT

L-leucine

Intervention Type DIETARY_SUPPLEMENT

leucine

4000 mg L-leucine per day for 24 weeks

Group Type PLACEBO_COMPARATOR

L-leucine

Intervention Type DIETARY_SUPPLEMENT

Interventions

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L-carnitine

Intervention Type DIETARY_SUPPLEMENT

L-leucine

Intervention Type DIETARY_SUPPLEMENT

Other Intervention Names

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L-carnitine-L-tartrate

Eligibility Criteria

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Inclusion Criteria

* must be able to swallow tablets

Exclusion Criteria

* cardiovascular disease
* liver disease
* kidney disease
* neuromuscular disease
* gastrointestinal disorders (including stomach ulcers and erosions)
* diabetes
* other severe chronic diseases
Minimum Eligible Age

18 Years

Maximum Eligible Age

29 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Medical University of Gdansk

OTHER

Sponsor Role collaborator

Gdansk University of Physical Education and Sport

OTHER

Sponsor Role lead

Responsible Party

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Robert Olek

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Other Identifiers

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2014/15/B/NZ7/00893

Identifier Type: OTHER_GRANT

Identifier Source: secondary_id

NCN_ROL

Identifier Type: -

Identifier Source: org_study_id

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