Effect of Amino Acid on Muscle Damage

NCT ID: NCT03319147

Last Updated: 2021-04-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-10-18

Study Completion Date

2019-10-30

Brief Summary

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The primary objective is to determine the impact of essential amino acids on integrated muscle protein synthesis over 4 days after resistance exercise.

In addition, the secondary objective is to determine the effect of essential amino acids on satellite cell regulation and inflammatory responses during this prolonged recovery period.

Detailed Description

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Conditions

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Healthy

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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Placebo

4g of maltodextrin

Group Type PLACEBO_COMPARATOR

Placebo

Intervention Type DIETARY_SUPPLEMENT

4g of maltdextrin

Active

4g of essential amino acids

Group Type ACTIVE_COMPARATOR

Active

Intervention Type DIETARY_SUPPLEMENT

4g of essential amino acids

Interventions

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Active

4g of essential amino acids

Intervention Type DIETARY_SUPPLEMENT

Placebo

4g of maltdextrin

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* Healthy, male, recreationally-active participants
* Healthy will be defined as screened by the PAR-Q+ (The Physical Activity Readiness Questionnaire for everyone; Appendix. B). Active will be defined as being in the top 20% of age specific scores on iPAQ (the International Physical Activity Questionnaire; Appendix.C).
* Participants are required not to engage in lower limb RT (resistance training) for at least 6 months prior to the study.
* Participants will be 18-35 years old.
* Participants are willing to abide by the compliance rules of this study

Exclusion Criteria

* Female
* Inability to adhere to any of the compliance rules judged by principle investigator or medical doctor
* Self-reported regular tobacco use
* Self-reported illicit drug use (e.g. growth hormone, testosterone, etc.)
* The individual who has allergy for milk
Minimum Eligible Age

18 Years

Maximum Eligible Age

35 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

Yes

Sponsors

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Ajinomoto Co., Inc.

INDUSTRY

Sponsor Role collaborator

University of Toronto

OTHER

Sponsor Role lead

Responsible Party

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Daniel Moore

Assistant Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Goldring Centre for High Performance Sport

Toronto, Ontario, Canada

Site Status

Countries

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Canada

Other Identifiers

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EAA

Identifier Type: -

Identifier Source: org_study_id

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