The Impact of Protein Intake on Protein Metabolism During Intensified Training
NCT ID: NCT02801344
Last Updated: 2019-03-29
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
12 participants
INTERVENTIONAL
2016-05-31
2018-02-28
Brief Summary
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Our recent study using the minimally invasive indicator amino acid oxidation (IAAO) technique have suggested that protein requirements in young men are at least 30% higher than the recommended protein intake.
The present study will investigate the impact of protein sufficiency on protein metabolism and performance during intensified training periods as a means to further our understanding of the nutritional requirements for the endurance athlete.
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
CROSSOVER
BASIC_SCIENCE
DOUBLE
Study Groups
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Normal protein intake
participants will receive the controlled-diet containing 0.8 g protein /kg/day and the test drink containing 0.14 g protein/kg/d.
Normal
test drink which contains low amount of amino acids (0.14 g/kg/day)
Controlled-diet
the diet containing 0.8 g protein /kg/day
Moderate protein intake
participants will receive the controlled-diet containing 1.20 g protein /kg/day and the test drink containing 0.40 g protein/kg/d.
Moderate
test drink which contains moderate amount of amino acids (0.40 g/kg/day)
Controlled-diet
the diet containing 0.8 g protein /kg/day
High protein intake
participants will receive the controlled-diet containing 1.83 g protein /kg/day and the test drink containing 1.03 g protein/kg/d.
High
test drink which contains high amount of amino acids (1.03 g/kg/day)
Controlled-diet
the diet containing 0.8 g protein /kg/day
Interventions
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Normal
test drink which contains low amount of amino acids (0.14 g/kg/day)
Moderate
test drink which contains moderate amount of amino acids (0.40 g/kg/day)
High
test drink which contains high amount of amino acids (1.03 g/kg/day)
Controlled-diet
the diet containing 0.8 g protein /kg/day
Eligibility Criteria
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Inclusion Criteria
* Participants who are categorized at least "very good" based on a study by Shvartz \& Reibold \[40\], in which peak rate of oxygen consumption(VO2 Peak) is used as an index. (i.e. the participants whose VO2peak is ≥57 ml/kg/min (18-24 y), ≥54 ml/kg/min (25-29 y), ≥52 ml/kg/min (30-34 y), ≥49 ml/kg/min (35-39 y), ≥47 ml/kg/min (40-44 y), ≥44 ml/kg/min (45-50 y) according to his age,
* Participants who can cover 10 km in less than 60 min after the VO2peak test and 5 km Time trial on session 2.
* Participants will be 18-50 years old.
* Participants are willing to abide by the compliance rules of this study
Exclusion Criteria
* Female
* Inability to adhere to any of the compliance rules judged by principal investigator or medical doctor
* Regular tobacco use
* Illicit drug use (e.g. growth hormone, testosterone, etc.)
18 Years
50 Years
MALE
Yes
Sponsors
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Ajinomoto Co., Inc.
INDUSTRY
University of Toronto
OTHER
Responsible Party
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Daniel Moore
Associate professor
Principal Investigators
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Daniel Moore, Ph.D.
Role: PRINCIPAL_INVESTIGATOR
Faculty of Kinesiology and Physical Education, University of Toronto
Locations
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Goldring Centre For High Performance Sport
Toronto, Ontario, Canada
Countries
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References
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Williamson E, Kato H, Volterman KA, Suzuki K, Moore DR. Greater plasma essential amino acids and lower 3-methylhistidine with higher protein intake during endurance training: a randomised control trial. Amino Acids. 2023 Oct;55(10):1285-1291. doi: 10.1007/s00726-022-03210-z. Epub 2022 Dec 7.
Other Identifiers
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PFE
Identifier Type: -
Identifier Source: org_study_id
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