Protein Requirements for Active Adolescent Females

NCT ID: NCT02800239

Last Updated: 2019-04-01

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 7 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2016-02-29
• Study Completion Date: 2017-12-31

Brief Summary

Protein requirements in active individuals have been suggested to be greater than the current recommended dietary allowance (RDA).

Nutritional requirements for dietary amino acids in adolescents have traditionally been determined utilizing the nitrogen balance technique, which is prone to underestimating protein requirements. As a result, there is a need to re-evaluate recommendations in order to characterize how dietary amino acid needs may be modulated by physical activity.

Recent studies using the minimally invasive indicator amino acid oxidation (IAAO) technique have suggested that protein requirements in young men are at least 50% higher than the RDA based on nitrogen balance data.

The purpose of this study is to measure the protein requirement in adolescent, females using the IAAO technique in the presence of a variable intensity exercise stimulus.

Conditions

Increased Metabolic Requirement; Healthy

Study Design

• Allocation Method: NA
• Intervention Model: SINGLE_GROUP
• Primary Study Purpose: BASIC_SCIENCE
• Blinding Strategy: NONE

Study Groups

Active, adolescent females

Subjects will receive different levels of amino acid intakes, varying from 0.2-2.67 g/kg/d

Group Type: EXPERIMENTAL

Amino Acid Intake

Intervention Type: DIETARY_SUPPLEMENT

Amino acid intakes will be varied at 0.2-2.67 g/kg/d

Interventions

Amino Acid Intake

Amino acid intakes will be varied at 0.2-2.67 g/kg/d

Intervention Type: DIETARY_SUPPLEMENT

Eligibility Criteria

Inclusion Criteria

• Healthy, active adolescent who regularly participates in moderate to vigorous physical activity 5 times a week for a minimum of 1 hour.
• Being -0.5 to +1.0 years from peak height velocity, determined by the ratio of standing to sitting height, with the maximal age for adolescents being 16 years.

Obtaining a minimum level of 5.8 on the Beep Test

Exclusion Criteria

• Inability to meet health and physical activity guidelines according to the Physical Activity Readiness Questionnaire (PAR-Q+) and Physical Activity Questionnaire,
• An inability to adhere to any of the protocol guidelines (i.e. caffeine consumption)
• A biological age falling outside of the aforementioned ranges

• Minimum Eligible Age: 10 Years
• Maximum Eligible Age: 15 Years
• Eligible Sex: FEMALE
• Accepts Healthy Volunteers: Yes

Sponsors

Ajinomoto Co., Inc.

INDUSTRY

Sponsor Role: collaborator

University of Toronto

OTHER

Sponsor Role: lead

Responsible Party

Daniel Moore

Assistant Professor

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Daniel Moore, PhD

Role: PRINCIPAL_INVESTIGATOR

University of Toronto

Locations

Goldring Centre for High Performance Sport

Toronto, Ontario, Canada

Countries

Canada

Other Identifiers

IAAO-AF

Identifier Type: -

Identifier Source: org_study_id